HLA-D in the rheumatic diseases

P. Stastny

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

HLA-Dw4 was first defined in our laboratory with homozygous typing cells from a patient with rheumatoid arthritis. The antigen was found in 13% of normal white persons and in 52% of white, factor-positive patients with adult onset rheumatoid arthritis. Homozygosity for HLA-Dw4 was increased in rheumatoid arthritis but not beyond that expected from the gene frequency. Childhood rheumatoid arthritis presents clinical variants with different HLA associations. HLA-Dw4 is rare in North American Blacks and was not increased in Black patients with rheumatoid arthritis.

Original languageEnglish (US)
Pages (from-to)601-607
Number of pages7
JournalRES Journal of the Reticuloendothelial Society
Volume26
Issue numberSUPPL.
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Hematology

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