HLA in Singapore Chinese with rheumatoid arthritis

M. L. Boey, G. B. Wee, C. Mohan, H. S. Howe, S. H. Chan, P. H. Feng

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The HLA-A, B, C, DR and DQ antigens were determined in 50 Singapore Chinese patients with rheumatoid arthritis (RA). There was a significant increase in the prevalence of HLA-Bw46, DRw53 and DQ3 in patients with RA. The linkage disequilibrium between Bw46 and DRw53 explains this association. This major histocompatibility complex association differs from the HLA-DR4 link in Caucasian populations and suggests that RA is an immunogenetically heterogeneous disease.

Original languageEnglish (US)
Pages (from-to)1517-1519
Number of pages3
JournalJournal of Rheumatology
Volume19
Issue number10
StatePublished - 1992

Fingerprint

Singapore
Rheumatoid Arthritis
HLA-DR4 Antigen
HLA-A Antigens
HLA-B Antigens
Linkage Disequilibrium
Major Histocompatibility Complex
Antigens
Population

Keywords

  • Chinese
  • HLA
  • rheumatoid arthritis

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Boey, M. L., Wee, G. B., Mohan, C., Howe, H. S., Chan, S. H., & Feng, P. H. (1992). HLA in Singapore Chinese with rheumatoid arthritis. Journal of Rheumatology, 19(10), 1517-1519.

HLA in Singapore Chinese with rheumatoid arthritis. / Boey, M. L.; Wee, G. B.; Mohan, C.; Howe, H. S.; Chan, S. H.; Feng, P. H.

In: Journal of Rheumatology, Vol. 19, No. 10, 1992, p. 1517-1519.

Research output: Contribution to journalArticle

Boey, ML, Wee, GB, Mohan, C, Howe, HS, Chan, SH & Feng, PH 1992, 'HLA in Singapore Chinese with rheumatoid arthritis', Journal of Rheumatology, vol. 19, no. 10, pp. 1517-1519.
Boey ML, Wee GB, Mohan C, Howe HS, Chan SH, Feng PH. HLA in Singapore Chinese with rheumatoid arthritis. Journal of Rheumatology. 1992;19(10):1517-1519.
Boey, M. L. ; Wee, G. B. ; Mohan, C. ; Howe, H. S. ; Chan, S. H. ; Feng, P. H. / HLA in Singapore Chinese with rheumatoid arthritis. In: Journal of Rheumatology. 1992 ; Vol. 19, No. 10. pp. 1517-1519.
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