Hospital course and short-term outcomes of term and late preterm neonates following exposure to prolonged rupture of membranes and/or chorioamnionitis

Gregory L. Jackson, Patricia Rawiki, Dorothy Sendelbach, M. Denise Manning, William D. Engle

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Our objective was to characterize the hospital course and short-term outcomes of neonates exposed to prolonged rupture of membranes (PROM), chorioamnionitis (CH), or both PROM and CH. Outcomes were positive blood culture and/or clinical signs of infection (+BC/CSI) prompting >4 days of antibiotics. Six neonates had a positive BC, 2 (0.6%) in the CH group and 4 (2.7%) in the PROM + CH group (P = 0.05); none of the neonates exposed to PROM alone had a +BC. These results support our current approach of withholding routine antibiotic therapy in neonates exposed to PROM alone.

Original languageEnglish (US)
Pages (from-to)89-90
Number of pages2
JournalPediatric Infectious Disease Journal
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2012

Keywords

  • chorioamnionitis
  • early onset neonatal sepsis
  • group B streptococcus
  • neonate
  • prolonged rupture of membranes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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