Specialized DNA polymerases are required in both prokaryotic and eukaryotic cells for bypassing sites of template DNA damage that arrest high-fidelity DNA replication. Recent studies in the literature provide hints of the complexity of DNA switching between polymerases for translesion DNA synthesis (TLS) and those for normal DNA replication.
- Polymerase switching
- Post-translational modification
- Xeroderma pigmentosum
ASJC Scopus subject areas
- Molecular Biology