How to build and interpret a nomogram for cancer prognosis

Alexia Iasonos, Deborah Schrag, Ganesh V. Raj, Katherine S. Panageas

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Nomograms are widely used for cancer prognosis, primarily because of their ability to reduce statistical predictive models into a single numerical estimate of the probability of an event, such as death or recurrence, that is tailored to the profile of an individual patient. User-friendly graphical interfaces for generating these estimates facilitate the use of nomograms during clinical encounters to inform clinical decision making. However, the statistical underpinnings of these models require careful scrutiny, and the degree of uncertainty surrounding the point estimates requires attention. This guide provides a nonstatistical audience with a methodological approach for building, interpreting, and using nomograms to estimate cancer prognosis or other health outcomes.

Original languageEnglish (US)
Pages (from-to)1346-1354
Number of pages9
JournalJournal of Clinical Oncology
Volume26
Issue number8
DOIs
StatePublished - Mar 10 2008

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Nomograms
Statistical Models
Neoplasms
Uncertainty
Recurrence
Health

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

How to build and interpret a nomogram for cancer prognosis. / Iasonos, Alexia; Schrag, Deborah; Raj, Ganesh V.; Panageas, Katherine S.

In: Journal of Clinical Oncology, Vol. 26, No. 8, 10.03.2008, p. 1346-1354.

Research output: Contribution to journalArticle

Iasonos, Alexia ; Schrag, Deborah ; Raj, Ganesh V. ; Panageas, Katherine S. / How to build and interpret a nomogram for cancer prognosis. In: Journal of Clinical Oncology. 2008 ; Vol. 26, No. 8. pp. 1346-1354.
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