DURING the month of December, 1978, the Howard Hughes Medical Institute is celebrating the 25th anniversary of its founding. It is appropriate to review the circumstances that surrounded the conception of this research institute as well as some of the early decisions related to the development of its scientific staff and research program. Throughout his lifetime Mr. Hughes expressed a continuing interest in medical research and as early as 1926 contemplated the establishment of an institute for this purpose. Dr. Verne Mason, then professor of clinical medicine at the University of Southern California and a graduate of the Johns Hopkins. . .
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