Human hippocampal theta oscillations

Distinctive features and interspecies commonalities

Joshua Jacobs, Bradley Lega, Andrew J. Watrous

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The hippocampus, along with its characteristic theta oscillation, has been widely implicated in various aspects of animal memory and behavior. Given the important roles that hippocampal theta oscillations have in theoretical models of brain function, it might be considered surprising that these signals have not been reported as often in humans as in animals. In this chapter we review recent research on hippocampal theta oscillations in humans, focusing on brain recordings from neurosurgical patients, which provide a key opportunity for observing hippocampal oscillations during cognition. The emerging theme of this body of work is that humans do indeed have hippocampal oscillations that are similar overall compared to the theta oscillation that is commonly found in rodents. Most notably, the human theta oscillation exhibits correlations with sensorimotor, navigation, and memory processing in the same general fashion as expected from rodents. However, some of the details of theta's relationship with behavior differ significantly compared to such signals in rodents-such as having a lower amplitude, frequency, and duration-which can make this signal less readily observable. Thus, theta oscillations are a key component of hippocampal processing in humans, but the patterns it exhibits compared to rodents point out distinctive aspects of human brain processes.

Original languageEnglish (US)
Title of host publicationThe Hippocampus from Cells to Systems
Subtitle of host publicationStructure, Connectivity, and Functional Contributions to Memory and Flexible Cognition
PublisherSpringer International Publishing
Pages37-67
Number of pages31
ISBN (Electronic)9783319504063
ISBN (Print)9783319504056
DOIs
StatePublished - Jan 1 2017

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oscillation
Rodentia
rodents
Brain
brain
Animal Behavior
Cognition
Hippocampus
Theoretical Models
hippocampus
cognition
animals
Research
duration

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)
  • Agricultural and Biological Sciences(all)
  • Psychology(all)

Cite this

Jacobs, J., Lega, B., & Watrous, A. J. (2017). Human hippocampal theta oscillations: Distinctive features and interspecies commonalities. In The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition (pp. 37-67). Springer International Publishing. https://doi.org/10.1007/978-3-319-50406-3_2

Human hippocampal theta oscillations : Distinctive features and interspecies commonalities. / Jacobs, Joshua; Lega, Bradley; Watrous, Andrew J.

The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition. Springer International Publishing, 2017. p. 37-67.

Research output: Chapter in Book/Report/Conference proceedingChapter

Jacobs, J, Lega, B & Watrous, AJ 2017, Human hippocampal theta oscillations: Distinctive features and interspecies commonalities. in The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition. Springer International Publishing, pp. 37-67. https://doi.org/10.1007/978-3-319-50406-3_2
Jacobs J, Lega B, Watrous AJ. Human hippocampal theta oscillations: Distinctive features and interspecies commonalities. In The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition. Springer International Publishing. 2017. p. 37-67 https://doi.org/10.1007/978-3-319-50406-3_2
Jacobs, Joshua ; Lega, Bradley ; Watrous, Andrew J. / Human hippocampal theta oscillations : Distinctive features and interspecies commonalities. The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition. Springer International Publishing, 2017. pp. 37-67
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