Hydrocodone for cough in advanced cancer

Jade Homsi, Declan Walsh, Kristine A. Nelson, Susan B. Legrand, Mellar Davis

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Cough is a common symptom in advanced cancer. Hydrocodone is the antitussive of choice in our palliative medicine inpatient unit. We reviewed the pharmacy records for the use of hydrocodone for all cancer admissions to our unit from May 1996 to December 1998. Median treatment duration with hydrocodone was three days (range 1-18). Median maximum daily dose was 15 mg (range 5-100), and median total dose during the hospital stay was 32 mg (range 5-455). Lung cancer as a primary cancer site was strongly related to the use of hydrocodone. The highest median duration of treatment (five days) was for esophageal cancer and the highest median maximum daily dose (35 mg) and total dose (75 mg) were for treating kidney cancer. This retrospective review provides information regarding the use of hydrocodone on the palliative medicine unit of the Cleveland Clinic Foundation. Controlled trials are needed to evaluate the efficacy and safety of hydrocodone for cough in advanced cancer.

Original languageEnglish (US)
Pages (from-to)342-346
Number of pages5
JournalAmerican Journal of Hospice and Palliative Medicine
Volume17
Issue number5
DOIs
StatePublished - Jan 1 2000

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Hydrocodone
Cough
Neoplasms
Antitussive Agents
Kidney Neoplasms
Esophageal Neoplasms
Inpatients
Length of Stay
Lung Neoplasms
Safety
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hydrocodone for cough in advanced cancer. / Homsi, Jade; Walsh, Declan; Nelson, Kristine A.; Legrand, Susan B.; Davis, Mellar.

In: American Journal of Hospice and Palliative Medicine, Vol. 17, No. 5, 01.01.2000, p. 342-346.

Research output: Contribution to journalArticle

Homsi, Jade ; Walsh, Declan ; Nelson, Kristine A. ; Legrand, Susan B. ; Davis, Mellar. / Hydrocodone for cough in advanced cancer. In: American Journal of Hospice and Palliative Medicine. 2000 ; Vol. 17, No. 5. pp. 342-346.
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