Hyperaggregation of platelets in intestinal tuberculosis: Role of platelets in chronic inflammation

R. Sarode, D. Bhasin, N. Marwaha, P. Roy, K. Singh, D. Panigrahi, G. Garewal, S. K. Mehta

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Eighty-eight percent (38/43) patients of intestinal tuberculosis showed significant hyperaggregation of platelets (P < 0.001). Serum and plasma from 15 patients when incubated with normal platelets caused hyperaggregation. Gel filtered platelets from 2 patients suspended in normal plasma showed hyperaggregation of platelets with arachidonic acid. Tubercular protein had no effect on platelet aggregation. A role of hyperactive platelets in chronic inflammatory response is discussed.

Original languageEnglish (US)
Pages (from-to)52-54
Number of pages3
JournalAmerican Journal of Hematology
Volume48
Issue number1
DOIs
StatePublished - 1995

Fingerprint

Tuberculosis
Blood Platelets
Inflammation
Platelet Aggregation
Arachidonic Acid
Gels
Serum
Proteins

Keywords

  • Acid fast bacilli
  • Inflammation
  • Platelet aggregation
  • Tuberculosis

ASJC Scopus subject areas

  • Hematology

Cite this

Hyperaggregation of platelets in intestinal tuberculosis : Role of platelets in chronic inflammation. / Sarode, R.; Bhasin, D.; Marwaha, N.; Roy, P.; Singh, K.; Panigrahi, D.; Garewal, G.; Mehta, S. K.

In: American Journal of Hematology, Vol. 48, No. 1, 1995, p. 52-54.

Research output: Contribution to journalArticle

Sarode, R, Bhasin, D, Marwaha, N, Roy, P, Singh, K, Panigrahi, D, Garewal, G & Mehta, SK 1995, 'Hyperaggregation of platelets in intestinal tuberculosis: Role of platelets in chronic inflammation', American Journal of Hematology, vol. 48, no. 1, pp. 52-54. https://doi.org/10.1002/ajh.2830480111
Sarode, R. ; Bhasin, D. ; Marwaha, N. ; Roy, P. ; Singh, K. ; Panigrahi, D. ; Garewal, G. ; Mehta, S. K. / Hyperaggregation of platelets in intestinal tuberculosis : Role of platelets in chronic inflammation. In: American Journal of Hematology. 1995 ; Vol. 48, No. 1. pp. 52-54.
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