Hyperaggregation of platelets in intestinal tuberculosis: Role of platelets in chronic inflammation

R. Sarode, D. Bhasin, N. Marwaha, P. Roy, K. Singh, D. Panigrahi, G. Garewal, S. K. Mehta

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Eighty‐eight percent (38/43) patients of intestinal tuberculosis showed significant hyperaggregation of platelets (P < 0.001). Serum and plasma from 15 patients when incubated with normal platelets caused hyperaggregation. Gel filtered platelets from 2 patients suspended in normal plasma showed hyperaggregation of platelets with arachidonic acid. Tubercular protein had no effect on platelet aggregation. A role of hyperactive platelets in chronic inflammatory response is discussed. ©1995 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)52-54
Number of pages3
JournalAmerican Journal of Hematology
Volume48
Issue number1
DOIs
StatePublished - Jan 1995

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Keywords

  • acid fast bacilli
  • inflammation
  • platelet aggregation
  • tuberculosis

ASJC Scopus subject areas

  • Hematology

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