Hyperphosphatemia in tumor lysis syndrome: the role of hemodialysis and continuous veno-venous hemofiltration

Abdullah Sakarcan, Raymond Quigley

Research output: Contribution to journalArticle

52 Scopus citations

Abstract

We report a 4-year-old boy who developed tumor lysis syndrome complicated by severe hyperphosphatemia and acute renal failure, following chemotherapy for T-cell acute lymphoblastic leukemia. Despite successful treatment of hyperphosphatemia with hemodialysis, there was an immediate rebound in the high serum phosphorus level. The patient underwent a second treatment with hemodialysis which was then followed by continuous veno-venous hemofiltration (CVVH). CVVH maintained his serum phosphorus at a stable level until his renal function improved. CVVH can be used in conjunction with hemodialysis to successfully treat the hyperphosphatemia associated with tumor lysis syndrome.

Original languageEnglish (US)
Pages (from-to)351-353
Number of pages3
JournalPediatric Nephrology
Volume8
Issue number3
DOIs
StatePublished - Jun 1 1994

Keywords

  • Acute renal failure
  • Continuous veno-venous hemofiltration
  • Hemodialysis
  • Hyperphosphatemia
  • Tumor lysis syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

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