Hyperspectral retinal imaging with a spectrally tunable light source

Robert P. Francis, Karel J. Zuzak, Rafael Ufret-Vincenty

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations


Hyperspectral retinal imaging can measure oxygenation and identify areas of ischemia in human patients, but the devices used by current researchers are inflexible in spatial and spectral resolution. We have developed a flexible research prototype consisting of a DLP®-based spectrally tunable light source coupled to a fundus camera to quickly explore the effects of spatial resolution, spectral resolution, and spectral range on hyperspectral imaging of the retina. The goal of this prototype is to (1) identify spectral and spatial regions of interest for early diagnosis of diseases such as glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy (DR); and (2) define required specifications for commercial products. In this paper, we describe the challenges and advantages of using a spectrally tunable light source for hyperspectral retinal imaging, present clinical results of initial imaging sessions, and describe how this research can be leveraged into specifying a commercial product.

Original languageEnglish (US)
Title of host publicationEmerging Digital Micromirror Device Based Systems and Applications III
StatePublished - Apr 14 2011
EventEmerging Digital Micromirror Device Based Systems and Applications III - San Francisco, CA, United States
Duration: Jan 26 2011Jan 26 2011

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


OtherEmerging Digital Micromirror Device Based Systems and Applications III
Country/TerritoryUnited States
CitySan Francisco, CA


  • Hyperspectral imaging
  • Ophthalmology
  • Tunable light source

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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