Hyperuricemic renal failure in nonhematologic solid tumors: A case report and review of the literature

Neeraj Saini, Kyeong Pyo Lee, Smita Jha, Sanket Patel, Neelima Bonthu, Ankit Kansagra, Ashmeet Bhatia, Sandra E. Martinez, Jaymin Patel, Sarah Altamimi, Sara Ghotb

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Tumor lysis syndrome (TLS) is an oncologic emergency that is caused by massive tumor cell lysis. It is commonly associated with hematological cancers like leukemia and lymphoma and uncommonly with solid nonhematologic tumors as well. However, spontaneous tumor lysis syndrome (STLS) without any cytotoxic chemotherapy rarely occurs in solid tumors. We describe a case of STLS in a metastatic adenocarcinoma of unknown primary and review the literature of STLS in solid non-hematologic tumors to identify various risk factors for pathogenesis of this entity.

Original languageEnglish (US)
Article number314056
JournalCase Reports in Medicine
Volume2012
DOIs
StatePublished - 2012

ASJC Scopus subject areas

  • Medicine(all)

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