Hypoglossal Schwannoma of Neck: Case Report and Review of Literature

Aaron Plitt, Tarek Y. El Ahmadieh, Shivani Bindal, Larry Myers, Jonathan White, Wayne Gluf

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background Schwannomas are benign, slow-growing neoplasms of the myelin-producing Schwann cells of peripheral nervous system that most commonly affect sensory nerves. Hypoglossal schwannomas, tumors of purely motor nerves, comprise <5% of all head and neck schwannomas. Since the first description of a hypoglossal schwannoma in 1933, there have been few case reports of extracranial origins. The most common location of an extracranial hypoglossal schwannoma is in the parapharyngeal space and can mimic paragangliomas. We describe the case of a woman presenting with an enlarging neck mass originally thought to be a paraganglioma but ultimately discovered to be a hypoglossal schwannoma at surgery. Case Description A 63-year-old woman had a well-circumscribed, mobile, nontender, 3-cm firm mass at the mandibular angle. On computed tomography, the mass was at the level of the carotid bifurcation, splaying the branching vessels. It was further evaluated with magnetic resonance imaging, which revealed a homogeneous, T2-hyperintense, T1-isointense mass with homogeneous contrast enhancement and scant flow voids. Biopsy revealed a spindle cell mass with positive S-100 staining. She underwent resection with the mass originating from the hypoglossal nerve. Conclusions Hypoglossal schwannomas are rare lesions with a variable location along the course of the nerve. An extracranial lesion was described here, which was initially mistaken for a paraganglioma. Surgical resection is the consensus recommendation and is often well tolerated with low risk of long-term recurrence.

Original languageEnglish (US)
Pages (from-to)240-243
Number of pages4
JournalWorld Neurosurgery
Volume110
DOIs
StatePublished - Feb 1 2018

Fingerprint

Neurilemmoma
Neck
Paraganglioma
Hypoglossal Nerve
Schwann Cells
Peripheral Nervous System
Myelin Sheath
Neoplasms
Head
Tomography
Magnetic Resonance Imaging
Staining and Labeling
Biopsy
Recurrence

Keywords

  • Hypoglossal nerve
  • Paraganglioma
  • Schwannoma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Hypoglossal Schwannoma of Neck : Case Report and Review of Literature. / Plitt, Aaron; El Ahmadieh, Tarek Y.; Bindal, Shivani; Myers, Larry; White, Jonathan; Gluf, Wayne.

In: World Neurosurgery, Vol. 110, 01.02.2018, p. 240-243.

Research output: Contribution to journalArticle

Plitt, Aaron ; El Ahmadieh, Tarek Y. ; Bindal, Shivani ; Myers, Larry ; White, Jonathan ; Gluf, Wayne. / Hypoglossal Schwannoma of Neck : Case Report and Review of Literature. In: World Neurosurgery. 2018 ; Vol. 110. pp. 240-243.
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