TY - JOUR
T1 - Hypokalemic paralyses
T2 - A review of the etiologies, pathophysiology, presentation, and therapy
AU - Stedwell, Ray E.
AU - Allen, Kevin M.
AU - Binder, Louis S.
PY - 1992/3
Y1 - 1992/3
N2 - Acute hypokalemic paralysis is an uncommon cause of acute weakness. Morbidity and mortality associated with unrecognized disease include resplratory failure and death. Hence, it is imperative for physicians to be knowledgeable about the causes of hypokalemic paralysis, and consider them diagnostically. The hypokalemic paralyses represent a heterogenoous group of disorders with a final common pathway presenting as acute weakness and hypokalemia. Most cases are due to familial hypokalemic paralysis; however, sporadic cases are associated with diverse underlying etiologies including thyrotoxic periodic paralysis, barium polsoning, renal tubular acidosis, primary hyperaldosteronism, licorice ingestion, and gastrointestinal potassium losses. The approach to the patient with hypokalemic paralysis includes a vigorous search for the underlying etiology and potassium replacement therapy. Further therapy depends on the etiology of the hypokalemia. Disposition depends on severity of symptoms, degree of hypokalemia, and chronicity of disease.
AB - Acute hypokalemic paralysis is an uncommon cause of acute weakness. Morbidity and mortality associated with unrecognized disease include resplratory failure and death. Hence, it is imperative for physicians to be knowledgeable about the causes of hypokalemic paralysis, and consider them diagnostically. The hypokalemic paralyses represent a heterogenoous group of disorders with a final common pathway presenting as acute weakness and hypokalemia. Most cases are due to familial hypokalemic paralysis; however, sporadic cases are associated with diverse underlying etiologies including thyrotoxic periodic paralysis, barium polsoning, renal tubular acidosis, primary hyperaldosteronism, licorice ingestion, and gastrointestinal potassium losses. The approach to the patient with hypokalemic paralysis includes a vigorous search for the underlying etiology and potassium replacement therapy. Further therapy depends on the etiology of the hypokalemia. Disposition depends on severity of symptoms, degree of hypokalemia, and chronicity of disease.
KW - Hypokalemia
KW - paralysis
KW - weakness
UR - http://www.scopus.com/inward/record.url?scp=0026594659&partnerID=8YFLogxK
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U2 - 10.1016/0735-6757(92)90048-3
DO - 10.1016/0735-6757(92)90048-3
M3 - Review article
C2 - 1586409
AN - SCOPUS:0026594659
SN - 0735-6757
VL - 10
SP - 143
EP - 148
JO - American Journal of Emergency Medicine
JF - American Journal of Emergency Medicine
IS - 2
ER -