Iatrogenic myocardial edema with potassium cardioplegia

R. P. Foglia, D. L. Steed, D. M. Follette, E. DeLand, G. D. Buckberg

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Postischemic myocardial edema depresses left ventricular function and coronary perfusion. Pharmacologic cardioplegia is being used increasingly to enhance myocardial protection during cardiac operations. In the present study we varied the colloid osmotic and osmotic pressures and the infusion pressures of four cardioplegic solutions to determine their respective roles in producing or preventing myocardial edema in a nonischemic setting. We found that myocardial edema during potassium cardioplegia is independent of infusion pressures, is caused by isosmotic crystalloid solutions, is worsened by hyposmolar crystalloid solutions, is avoided by the addition of colloid, and is avoided if the solution is made hyperosmotic with the addition of mannitol.

Original languageEnglish (US)
Pages (from-to)217-222
Number of pages6
JournalJournal of Thoracic and Cardiovascular Surgery
Volume78
Issue number2
StatePublished - 1979

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Induced Heart Arrest
Edema
Potassium
Colloids
Cardioplegic Solutions
Pressure
Osmotic Pressure
Mannitol
Left Ventricular Function
Perfusion
crystalloid solutions

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Foglia, R. P., Steed, D. L., Follette, D. M., DeLand, E., & Buckberg, G. D. (1979). Iatrogenic myocardial edema with potassium cardioplegia. Journal of Thoracic and Cardiovascular Surgery, 78(2), 217-222.

Iatrogenic myocardial edema with potassium cardioplegia. / Foglia, R. P.; Steed, D. L.; Follette, D. M.; DeLand, E.; Buckberg, G. D.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 78, No. 2, 1979, p. 217-222.

Research output: Contribution to journalArticle

Foglia, RP, Steed, DL, Follette, DM, DeLand, E & Buckberg, GD 1979, 'Iatrogenic myocardial edema with potassium cardioplegia', Journal of Thoracic and Cardiovascular Surgery, vol. 78, no. 2, pp. 217-222.
Foglia RP, Steed DL, Follette DM, DeLand E, Buckberg GD. Iatrogenic myocardial edema with potassium cardioplegia. Journal of Thoracic and Cardiovascular Surgery. 1979;78(2):217-222.
Foglia, R. P. ; Steed, D. L. ; Follette, D. M. ; DeLand, E. ; Buckberg, G. D. / Iatrogenic myocardial edema with potassium cardioplegia. In: Journal of Thoracic and Cardiovascular Surgery. 1979 ; Vol. 78, No. 2. pp. 217-222.
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