Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265

John White, Satish K. Dhingra, Xiaoyi Deng, Farah El Mazouni, Marcus C.S. Lee, Gustavo A. Afanador, Aloysus Lawong, Diana R Tomchick, Caroline L. Ng, Jade Bath, Pradipsinh K. Rathod, David A. Fidock, Margaret A Phillips

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