Identification and whole genome sequencing of the first case of Kosakonia radicincitans causing a human bloodstream infection

Micah D. Bhatti, Awdhesh Kalia, Pranoti Sahasrabhojane, Jiwoong Kim, David E. Greenberg, Samuel A. Shelburne

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The taxonomy of Enterobacter species is rapidly changing. Herein we report a bloodstream infection isolate originally identified as Enterobacter cloacae by Vitek 2 methodology that we found to be Kosakonia radicincitans using genetic means. Comparative whole genome sequencing of our isolate and other published Kosakonia genomes revealed these organisms lack the AmpC β-lactamase present on the chromosome of Enterobacter sp. A fimbriae operon primarily found in Escherichia coli O157:H7 isolates was present in our organism and other available K. radicincitans genomes. This is the first report of a Kosakonia species, which are typically associated with plants, causing a human infection.

Original languageEnglish (US)
Article number62
JournalFrontiers in Microbiology
Volume8
Issue numberJAN
DOIs
StatePublished - Jan 24 2017

Keywords

  • AmpC
  • Bloodstream infection
  • Enterobacter
  • Fimbriae
  • Kosakonia radicincitans

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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