Identification of the interaction site within acyl-CoA:Cholesterol acyltransferase 2 for the isoform-specific inhibitor pyripyropene A

Medicine & Life Sciences

• pyripyropene A 100%
• sterol O-acyltransferase 2 88%
• Protein Isoforms 36%
• Amino Acids 13%
• Atherosclerosis 6%
• Hypercholesterolemia 3%
• Amino Acid Sequence 3%
• Proteins 2%
• Diet 2%
• Membranes 2%
• Mutation 2%
• Enzymes 2%
• Liver 1%
• Pharmaceutical Preparations 1%

Chemical Compounds

• Pyripyropene A 87%
• Acyl-CoA 58%
• Cholesterol 40%
• Acid 6%
• Hyperlipidemic 6%
• % Inhibition 4%
• Amino Acid Sequence 3%
• Mutation 3%
• Protein 3%
• Drug 1%