TY - JOUR
T1 - Idiopathic thrombocytopenic purpura
T2 - Beyond consensus
AU - Medeiros, Desiree
AU - Buchanan, George R.
PY - 2000/1/27
Y1 - 2000/1/27
N2 - Idiopathic thrombocytopenic purpura (ITP) is the most common acquired bleeding disorder encountered by pediatricians. Most children with ITP have minimal bleeding and complete platelet count recovery within weeks to months. Therapy for ITP has ranged from close observation without medical intervention to aggressive management with corticosteroids, intravenous immunoglobulin G, or anti-D immune globulin. The topic of ITP has incited great debate among practitioners, and this debate prompted the development of ITP practice guidelines by the British Paediatric Haematology Group in 1992 and by the American Society of Hematology in 1996. A better understanding of the clinical course of, risk for significant bleeding in, and optimal evaluation and therapy of childhood ITP will require carefully designed, multicenter, clinical trials.
AB - Idiopathic thrombocytopenic purpura (ITP) is the most common acquired bleeding disorder encountered by pediatricians. Most children with ITP have minimal bleeding and complete platelet count recovery within weeks to months. Therapy for ITP has ranged from close observation without medical intervention to aggressive management with corticosteroids, intravenous immunoglobulin G, or anti-D immune globulin. The topic of ITP has incited great debate among practitioners, and this debate prompted the development of ITP practice guidelines by the British Paediatric Haematology Group in 1992 and by the American Society of Hematology in 1996. A better understanding of the clinical course of, risk for significant bleeding in, and optimal evaluation and therapy of childhood ITP will require carefully designed, multicenter, clinical trials.
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U2 - 10.1097/00008480-200002000-00002
DO - 10.1097/00008480-200002000-00002
M3 - Review article
C2 - 10676767
AN - SCOPUS:0033968603
SN - 1040-8703
VL - 12
SP - 4
EP - 9
JO - Current opinion in pediatrics
JF - Current opinion in pediatrics
IS - 1
ER -