Imaging changes after stereotactic body radiation therapy for lung and liver tumors

Simon S. Lo, Bin S. Teh, Jian Z. Wang, Zhibin Huang, Jennifer Zook, Tracy Price, Nina A. Mayr, John C. Grecula, Robert D. Timmerman, Higinia R. Cardenes

Research output: Contribution to journalReview article

12 Scopus citations

Abstract

Stereotactic body radiation therapy (SBRT) is gaining wide acceptance as a treatment modality for lung and liver tumors, and it is crucial to make an accurate evaluation of the local effects of ablative doses of radiation in terms of local tumor control and normal tissue reaction or damage. The very complex radiation dose distribution of SBRT, the use of a large number of non-opposing and noncoplanar beams, and the delivery of individual ablative doses of radiation may cause substantially different radiographic appearance on diagnostic imaging compared with conventional radiation therapy. Different patterns of radiographic changes have been observed in the lung and liver after SBRT. This article reviews the post-SBRT imaging changes in the lung and liver. Since computed tomography and PET are the most commonly used diagnostic imaging tools for monitoring lung tumor and computed tomography for liver tumors, this article will focus on the changes observed on those imaging modalities.

Original languageEnglish (US)
Pages (from-to)613-620
Number of pages8
JournalExpert Review of Anticancer Therapy
Volume11
Issue number4
DOIs
StatePublished - Apr 1 2011

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Keywords

  • imaging changes
  • liver
  • lung
  • radiation
  • stereotactic

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)

Cite this

Lo, S. S., Teh, B. S., Wang, J. Z., Huang, Z., Zook, J., Price, T., Mayr, N. A., Grecula, J. C., Timmerman, R. D., & Cardenes, H. R. (2011). Imaging changes after stereotactic body radiation therapy for lung and liver tumors. Expert Review of Anticancer Therapy, 11(4), 613-620. https://doi.org/10.1586/era.10.164