Imaging of aortopulmonary collateral arteries with high-resolution multidetector CT

Gerald F. Greil, Max Schoebinger, Axel Kuettner, Juergen F. Schaefer, Florian Dammann, Claus D. Claussen, Michael Hofbeck, Hans Peter Meinzer, Ludger Sieverding

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Background: Precise visualization of the pulmonary vasculature is mandatory for adequate treatment of patients with pulmonary atresia and ventricular septal defect (PA-VSD). Aortopulmonary collateral arteries (APCs) can be visualized by selective injections of contrast agent in the catheterization laboratory. Objective: To evaluate multidetector CT (MDCT) and different image postprocessing methods for analysis of complex pulmonary blood supply in patients with PA-VSD. Materials and methods: Eight patients (6 weeks to 27.8 years of age) with PA-VSD and APCs underwent MDCT and cardiac catheterization. Using multiplanar reformatting, volume rendering and semiautomatic segmentation algorithms, the aorta, pulmonary arteries and APCs were displayed. MDCT and cardiac catheterization were analyzed by two independent observers. Results: MDCT accurately imaged central pulmonary arteries (n=8), aortopulmonary shunts (n=2), right ventricular to pulmonary artery conduits (n=2) and origin, course and intrapulmonary connections of APCs (n=25), compared to X-ray angiography. A high correlation was found between the MDCT vessel diameter measurements by two independent observers (n=70, r=0.96, P <0.01) and between MDCT and angiographic vessel diameter measurements (n=68, r=0.96, P <0.01). Conclusions: Using three-dimensional imaging software, a complex pulmonary blood supply can be non-invasively and accurately imaged with high-resolution MDCT. This technique may help to reduce the number of cardiac catheterizations or guide interventional or surgical therapy.

Original languageEnglish (US)
Pages (from-to)502-509
Number of pages8
JournalPediatric Radiology
Volume36
Issue number6
DOIs
Publication statusPublished - Jun 1 2006

    Fingerprint

Keywords

  • Aortopulmonary collateral arteries
  • Children
  • Congenital
  • Heart
  • Multidetector CT
  • Technique

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging

Cite this

Greil, G. F., Schoebinger, M., Kuettner, A., Schaefer, J. F., Dammann, F., Claussen, C. D., ... Sieverding, L. (2006). Imaging of aortopulmonary collateral arteries with high-resolution multidetector CT. Pediatric Radiology, 36(6), 502-509. https://doi.org/10.1007/s00247-006-0143-0