Imipramine and social-vocational adjustment in chronic depression

J. H. Kocsis, A. J. Frances, C. Voss, B. J. Mason, J. J. Mann, J. Sweeney

Research output: Contribution to journalArticle

70 Scopus citations


The authors compared the effects of 6 weeks of imipramine treatment with 6 weeks of placebo treatment on social and vocational impairment in chronic depression. Imipramine was associated with significantly greater pre- to posttreatment improvement of social-vocational impairments in chronic depression, suggesting that these impairments may have represented affective symptoms rather than characterologic deficits.

Original languageEnglish (US)
Pages (from-to)997-999
Number of pages3
JournalAmerican Journal of Psychiatry
Issue number8
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Psychiatry and Mental health

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    Kocsis, J. H., Frances, A. J., Voss, C., Mason, B. J., Mann, J. J., & Sweeney, J. (1988). Imipramine and social-vocational adjustment in chronic depression. American Journal of Psychiatry, 145(8), 997-999.