Immune response of guinea pig lymphoid cells in vitro. III. Induction by Concanavalin A of a secondary anti-TNP response in primed guinea pig cells

J. Kettman, S. Ben-Sasson

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Spleen and lymph node cells of 2,4,6-trinitrophenyl-ovalbumin (TNP-OVA)-primed guinea pigs, show a secondary anti-TNP plaque-forming cell (PFC) response on culture with Concanavalin A which does not require the addition of TNP-OVA but this response may be modestly stimulated by soluble TNP-OVA. If TNP sheep red blood cells (SRBC) are added instead as antigen, the spontaneous anti-TNP response is suppressed but an anti-SRBC response is induced.

Original languageEnglish (US)
Pages (from-to)216-223
Number of pages8
JournalCellular Immunology
Volume50
Issue number1
DOIs
StatePublished - Mar 1 1980

ASJC Scopus subject areas

  • Immunology

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