Immunologic maturation in utero

Kinetics of the primary antibody response in the fetal lamb

Arthur M. Silverstein, Charles J. Parshall, Jonathan W. Uhr

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The kinetics of the primary antibody response to bacteriophage φX174 have been studied in the fetal lamb in utero after permanent indwelling catheterization of the fetal blood vessels. The initial antibody response by the developing fetus to this form of antigenic stimulus is comparable to that found in adult animals and shows none of the characteristics of the immature immunologic response that have generally been ascribed to fetal and neonatal animals.

Original languageEnglish (US)
Pages (from-to)1677-1680
Number of pages4
JournalScience
Volume154
Issue number3757
StatePublished - 1966

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Antibody Formation
Newborn Animals
Fetal Blood
Catheterization
Bacteriophages
Blood Vessels
Fetus

ASJC Scopus subject areas

  • General

Cite this

Silverstein, A. M., Parshall, C. J., & Uhr, J. W. (1966). Immunologic maturation in utero: Kinetics of the primary antibody response in the fetal lamb. Science, 154(3757), 1677-1680.

Immunologic maturation in utero : Kinetics of the primary antibody response in the fetal lamb. / Silverstein, Arthur M.; Parshall, Charles J.; Uhr, Jonathan W.

In: Science, Vol. 154, No. 3757, 1966, p. 1677-1680.

Research output: Contribution to journalArticle

Silverstein, AM, Parshall, CJ & Uhr, JW 1966, 'Immunologic maturation in utero: Kinetics of the primary antibody response in the fetal lamb', Science, vol. 154, no. 3757, pp. 1677-1680.
Silverstein AM, Parshall CJ, Uhr JW. Immunologic maturation in utero: Kinetics of the primary antibody response in the fetal lamb. Science. 1966;154(3757):1677-1680.
Silverstein, Arthur M. ; Parshall, Charles J. ; Uhr, Jonathan W. / Immunologic maturation in utero : Kinetics of the primary antibody response in the fetal lamb. In: Science. 1966 ; Vol. 154, No. 3757. pp. 1677-1680.
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