Immunotherapy of melanoma: An update

Jade Homsi, Joshua C. Grimm, Patrick Hwu

Research output: Contribution to journalReview article

4 Scopus citations

Abstract

The incidence of melanoma has been increasing worldwide. A relationship between melanoma and the immune system was established years ago. Modulating the immune system in the management of different stages of melanoma has been the focus of numerous large randomized trials worldwide. This article reviews the current status of immunotherapy for melanoma, with a focus on the recent promising results from using vaccines, cytotoxic T-lymphocyte antigen-4 (CTLA-4) antibodies, and adoptive cell therapy.

Original languageEnglish (US)
Pages (from-to)145-163
Number of pages19
JournalSurgical Oncology Clinics of North America
Volume20
Issue number1
DOIs
StatePublished - Jan 1 2011

Keywords

  • CTLA-4
  • Immunotherapy
  • Interleukin
  • Melanoma
  • T cell
  • Vaccine

ASJC Scopus subject areas

  • Surgery
  • Oncology

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