Abstract
Many types of tumour cell express high levels of surface antigens which are largely absent from normal cells. Monoclonal antibodies against these surface antigens can be coupled to potent toxins to form conjugates (immunotoxins) which selectively kill the antigen-bearing cells. This article describes the components of immunotoxins, their modes of action and their clinical applications.
Original language | English (US) |
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Pages (from-to) | 175-179 |
Number of pages | 5 |
Journal | Trends in Biotechnology |
Volume | 3 |
Issue number | 7 |
DOIs | |
State | Published - Jul 1985 |
ASJC Scopus subject areas
- Biotechnology
- Bioengineering