Impact of early valve surgery on outcome of staphylococcus aureus prosthetic valve infective endocarditis

Analysis in the international collaboration of endocarditis-prospective cohort study

Catherine Chirouze, François Alla, Vance G. Fowler, Daniel J. Sexton, G. Ralph Corey, Vivian H. Chu, Andrew Wang, Marie Line Erpelding, Emanuele Durante-Mangoni, Nuria Fernández-Hidalgo, Efthymia Giannitsioti, Margaret M. Hannan, Tatjana Lejko-Zupanc, José M. Miró, Patricia Muñoz, David R. Murdoch, Pierre Tattevin, Christophe Tribouilloy, Bruno Hoen, Liliana Clara & 269 others Marisa Sanchez, Francisco Nacinovich, Pablo Fernandez Oses, Ricardo Ronderos, Adriana Sucari, Jorge Thierer, José Casabé, Claudia Cortes, Javier Altclas, Silvia Kogan, Denis Spelman, Eugene Athan, Owen Harris, Karina Kennedy, Ren Tan, David Gordon, Lito Papanicolas, Damon Eisen, Leeanne Grigg, Alan Street, Tony Korman, Despina Kotsanas, Robyn Dever, Pam Konecny, Richard Lawrence, David Rees, Suzanne Ryan, Michael P. Feneley, John Harkness, Phillip Jones, Jeffrey Post, Porl Reinbott, Rainer Gattringer, Franz Wiesbauer, Adriana Ribas Andrade, Ana Cláudia Passos De Brito, Armenio Costa Guimarães, Max Grinberg, Alfredo José Mansur, Rinaldo Focaccia Siciliano, Tania Mara Varejao Strabelli, Marcelo Luiz Campos Vieira, Regina Aparecida De Medeiros Tranchesi, Marcelo Goulart Paiva, Claudio Querido Fortes, Auristela De Oliveira Ramos, Giovanna Ferraiuoli, Wilma Golebiovski, Cristiane Lamas, Marisa Santos, Clara Weksler, James A. Karlowsky, Yoav Keynan, Andrew M. Morris, Ethan Rubinstein, Sandra Braun Jones, Patricia Garcia, M. Cereceda, Alberto Fica, Rodrigo Montagna Mella, Bruno Barsic, Suzana Bukovski, Vladimir Krajinovic, Ana Pangercic, Igor Rudez, Josip Vincelj, Tomas Freiberger, Jiri Pol, Barbora Zaloudikova, Ashour Zainab, Amani El Kholy, Marwa Mishaal, Hussien Rizk, Neijla Aissa, Corentine Alauzet, Catherine Campagnac, Thanh Doco-Lecompte, Christine Selton-Suty, Jean Paul Casalta, Pierre Edouard Fournier, Gilbert Habib, Didier Raoult, Franck Thuny, François Delahaye, Armelle Delahaye, Francois Vandenesch, Erwan Donal, Pierre Yves Donnio, Christian Michelet, Matthieu Revest, Jérémie Violette, Florent Chevalier, Antoine Jeu, Dan M D Rusinaru, Claire Sorel, Yvette Bernard, Joel Leroy, Patrick Plesiat, Christoph Naber, Carl Neuerburg, Bahram Mazaheri, Sofia Athanasia, Ioannis Deliolanis, Helen Giamarellou, Thomas Tsaganos, Elena Mylona, Olga Paniara, Konstantinos Papanicolaou, John Pyros, Athanasios Skoutelis, Gautam Sharma, Johnson Francis, Lathi Nair, Vinod Thomas, Krishnan Venugopal, John Hurley, Dan Gilon, Sarah Israel, Maya Korem, Jacob Strahilevitz, Roberta Casillo, Susanna Cuccurullo, Giovanni Dialetto, Mattucci Irene, Enrico Ragone, Marie Françoise Tripodi, Riccardo Utili, Enrico Cecchi, Francesco De Rosa, Davide Forno, Massimo Imazio, Rita Trinchero, Alessandro Tebini, Paolo Grossi, Mariangela Lattanzio, Antonio Toniolo, Antonio Goglio, Annibale Raglio, Veronica Ravasio, Marco Rizzi, Fredy Suter, Giampiero Carosi, Silvia Magri, Liana Signorini, Tania Baban, Zeina Kanafani, Souha S. Kanj, Mohamad Yasmine, Imran Abidin, Syahidah Syed Tamin, Eduardo Rivera Martínez, Gabriel Israel Soto Nieto, Jan T M Van Der Meer, Stephen Chambers, David Holland, Arthur Morris, Nigel Raymond, Kerry Read, Stefan Dragulescu, Adina Ionac, Cristian Mornos, O. M. Butkevich, Natalia Chipigina, Ozerecky Kirill, Kulichenko Vadim, Tatiana Vinogradova, Jameela Edathodu, Magid Halim, Luh Nah Lum, Ru San Tan, Mateja Logar, Manica Mueller-Premru, Patrick Commerford, Anita Commerford, Eduan Deetlefs, Cass Hansa, Mpiko Ntsekhe, Manuel Almela, Yolanda Armero, Manuel Azqueta, Ximena Castañeda, Carlos Cervera, Ana Del Rio, Carlos Falces, Cristina Garcia-De-La-Maria, Guillermina Fita, Jose M. Gatell, Francesc Marco, Carlos A. Mestres, Asuncion Moreno, Salvador Ninot, Carlos Paré, Joan Pericas, Jose Ramirez, Irene Rovira, Marta Sitges, Ignasi Anguera, Bernat Font, Joan Raimon Guma, Javier Bermejo, Emilio Bouza, Miguel Angel Garcia Fernández, Victor Gonzalez-Ramallo, Mercedes Marín, Miguel Pedromingo, Jorge Roda, Marta Rodríguez-Créixems, Jorge Solis, Benito Almirante, Pilar Tornos, Arístides De Alarcón, Ricardo Parra, Eric Alestig, Magnus Johansson, Lars Olaison, Ulrika Snygg-Martin, Orathai Pachirat, Pimchitra Pachirat, Burabha Pussadhamma, Vichai Senthong, Anna Casey, Tom Elliott, Peter Lambert, Richard Watkin, Christina Eyton, John L. Klein, Suzanne Bradley, Carol Kauffman, Roger Bedimo, Anna Lisa Crowley, Pamela Douglas, Laura Drew, Thomas Holland, Tahaniyat Lalani, Daniel Mudrick, Zaniab Samad, Martin Stryjewski, Christopher W. Woods, Stamatios Lerakis, Robert Cantey, Lisa Steed, Dannah Wray, Stuart A. Dickerman, Hector Bonilla, Joseph Di Persio, Sara Jane Salstrom, John Baddley, Mukesh Patel, Gail Peterson, Amy Stancoven, Luis Afonso, Theresa Kulman, Donald Levine, Michael Rybak, Christopher H. Cabell, Khaula Baloch, Christy C. Dixon, Tina Harding, Marian Jones-Richmond, Paul Pappas, Lawrence P. Park, Thomas Redick, Judy Stafford, Kevin Anstrom, Arnold S. Bayer, A. W. Karchmer, David T. Durack, Susannah Eykyn, Phillipe Moreillon

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Background. The impact of early valve surgery (EVS) on the outcome of Staphylococcus aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this study was to evaluate the association between EVS, performed within the first 60 days of hospitalization, and outcome of SA PVIE within the International Collaboration on Endocarditis-Prospective Cohort Study. Methods. Participants were enrolled between June 2000 and December 2006. Cox proportional hazards modeling that included surgery as a time-dependent covariate and propensity adjustment for likelihood to receive cardiac surgery was used to evaluate the impact of EVS and 1-year all-cause mortality on patients with definite left-sided S. aureus PVIE and no history of injection drug use. Results. EVS was performed in 74 of the 168 (44.3%) patients. One-year mortality was significantly higher among patients with S. aureus PVIE than in patients with non-S. aureus PVIE (48.2% vs 32.9%; P = .003). Staphylococcus aureus PVIE patients who underwent EVS had a significantly lower 1-year mortality rate (33.8% vs 59.1%; P = .001). In multivariate, propensity-adjusted models, EVS was not associated with 1-year mortality (risk ratio, 0.67 [95% confidence interval, .39-1.15]; P = .15). Conclusions. In this prospective, multinational cohort of patients with S. aureus PVIE, EVS was not associated with reduced 1-year mortality. The decision to pursue EVS should be individualized for each patient, based upon infection-specific characteristics rather than solely upon the microbiology of the infection causing PVIE.

Original languageEnglish (US)
Pages (from-to)741-749
Number of pages9
JournalClinical Infectious Diseases
Volume60
Issue number5
DOIs
StatePublished - 2015

Fingerprint

Endocarditis
Staphylococcus aureus
Cohort Studies
Prospective Studies
Mortality
Microbiology
Infection
Thoracic Surgery
Hospitalization
Odds Ratio
Confidence Intervals
Injections
Pharmaceutical Preparations

Keywords

  • 1-year mortality
  • Endocarditis
  • Prosthetic valve
  • Surgery

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

Cite this

Impact of early valve surgery on outcome of staphylococcus aureus prosthetic valve infective endocarditis : Analysis in the international collaboration of endocarditis-prospective cohort study. / Chirouze, Catherine; Alla, François; Fowler, Vance G.; Sexton, Daniel J.; Corey, G. Ralph; Chu, Vivian H.; Wang, Andrew; Erpelding, Marie Line; Durante-Mangoni, Emanuele; Fernández-Hidalgo, Nuria; Giannitsioti, Efthymia; Hannan, Margaret M.; Lejko-Zupanc, Tatjana; Miró, José M.; Muñoz, Patricia; Murdoch, David R.; Tattevin, Pierre; Tribouilloy, Christophe; Hoen, Bruno; Clara, Liliana; Sanchez, Marisa; Nacinovich, Francisco; Oses, Pablo Fernandez; Ronderos, Ricardo; Sucari, Adriana; Thierer, Jorge; Casabé, José; Cortes, Claudia; Altclas, Javier; Kogan, Silvia; Spelman, Denis; Athan, Eugene; Harris, Owen; Kennedy, Karina; Tan, Ren; Gordon, David; Papanicolas, Lito; Eisen, Damon; Grigg, Leeanne; Street, Alan; Korman, Tony; Kotsanas, Despina; Dever, Robyn; Konecny, Pam; Lawrence, Richard; Rees, David; Ryan, Suzanne; Feneley, Michael P.; Harkness, John; Jones, Phillip; Post, Jeffrey; Reinbott, Porl; Gattringer, Rainer; Wiesbauer, Franz; Andrade, Adriana Ribas; De Brito, Ana Cláudia Passos; Guimarães, Armenio Costa; Grinberg, Max; Mansur, Alfredo José; Siciliano, Rinaldo Focaccia; Strabelli, Tania Mara Varejao; Vieira, Marcelo Luiz Campos; De Medeiros Tranchesi, Regina Aparecida; Paiva, Marcelo Goulart; Fortes, Claudio Querido; De Oliveira Ramos, Auristela; Ferraiuoli, Giovanna; Golebiovski, Wilma; Lamas, Cristiane; Santos, Marisa; Weksler, Clara; Karlowsky, James A.; Keynan, Yoav; Morris, Andrew M.; Rubinstein, Ethan; Jones, Sandra Braun; Garcia, Patricia; Cereceda, M.; Fica, Alberto; Mella, Rodrigo Montagna; Barsic, Bruno; Bukovski, Suzana; Krajinovic, Vladimir; Pangercic, Ana; Rudez, Igor; Vincelj, Josip; Freiberger, Tomas; Pol, Jiri; Zaloudikova, Barbora; Zainab, Ashour; El Kholy, Amani; Mishaal, Marwa; Rizk, Hussien; Aissa, Neijla; Alauzet, Corentine; Campagnac, Catherine; Doco-Lecompte, Thanh; Selton-Suty, Christine; Casalta, Jean Paul; Fournier, Pierre Edouard; Habib, Gilbert; Raoult, Didier; Thuny, Franck; Delahaye, François; Delahaye, Armelle; Vandenesch, Francois; Donal, Erwan; Donnio, Pierre Yves; Michelet, Christian; Revest, Matthieu; Violette, Jérémie; Chevalier, Florent; Jeu, Antoine; Rusinaru, Dan M D; Sorel, Claire; Bernard, Yvette; Leroy, Joel; Plesiat, Patrick; Naber, Christoph; Neuerburg, Carl; Mazaheri, Bahram; Athanasia, Sofia; Deliolanis, Ioannis; Giamarellou, Helen; Tsaganos, Thomas; Mylona, Elena; Paniara, Olga; Papanicolaou, Konstantinos; Pyros, John; Skoutelis, Athanasios; Sharma, Gautam; Francis, Johnson; Nair, Lathi; Thomas, Vinod; Venugopal, Krishnan; Hurley, John; Gilon, Dan; Israel, Sarah; Korem, Maya; Strahilevitz, Jacob; Casillo, Roberta; Cuccurullo, Susanna; Dialetto, Giovanni; Irene, Mattucci; Ragone, Enrico; Tripodi, Marie Françoise; Utili, Riccardo; Cecchi, Enrico; De Rosa, Francesco; Forno, Davide; Imazio, Massimo; Trinchero, Rita; Tebini, Alessandro; Grossi, Paolo; Lattanzio, Mariangela; Toniolo, Antonio; Goglio, Antonio; Raglio, Annibale; Ravasio, Veronica; Rizzi, Marco; Suter, Fredy; Carosi, Giampiero; Magri, Silvia; Signorini, Liana; Baban, Tania; Kanafani, Zeina; Kanj, Souha S.; Yasmine, Mohamad; Abidin, Imran; Tamin, Syahidah Syed; Martínez, Eduardo Rivera; Nieto, Gabriel Israel Soto; Van Der Meer, Jan T M; Chambers, Stephen; Holland, David; Morris, Arthur; Raymond, Nigel; Read, Kerry; Dragulescu, Stefan; Ionac, Adina; Mornos, Cristian; Butkevich, O. M.; Chipigina, Natalia; Kirill, Ozerecky; Vadim, Kulichenko; Vinogradova, Tatiana; Edathodu, Jameela; Halim, Magid; Lum, Luh Nah; Tan, Ru San; Logar, Mateja; Mueller-Premru, Manica; Commerford, Patrick; Commerford, Anita; Deetlefs, Eduan; Hansa, Cass; Ntsekhe, Mpiko; Almela, Manuel; Armero, Yolanda; Azqueta, Manuel; Castañeda, Ximena; Cervera, Carlos; Del Rio, Ana; Falces, Carlos; Garcia-De-La-Maria, Cristina; Fita, Guillermina; Gatell, Jose M.; Marco, Francesc; Mestres, Carlos A.; Moreno, Asuncion; Ninot, Salvador; Paré, Carlos; Pericas, Joan; Ramirez, Jose; Rovira, Irene; Sitges, Marta; Anguera, Ignasi; Font, Bernat; Guma, Joan Raimon; Bermejo, Javier; Bouza, Emilio; Fernández, Miguel Angel Garcia; Gonzalez-Ramallo, Victor; Marín, Mercedes; Pedromingo, Miguel; Roda, Jorge; Rodríguez-Créixems, Marta; Solis, Jorge; Almirante, Benito; Tornos, Pilar; De Alarcón, Arístides; Parra, Ricardo; Alestig, Eric; Johansson, Magnus; Olaison, Lars; Snygg-Martin, Ulrika; Pachirat, Orathai; Pachirat, Pimchitra; Pussadhamma, Burabha; Senthong, Vichai; Casey, Anna; Elliott, Tom; Lambert, Peter; Watkin, Richard; Eyton, Christina; Klein, John L.; Bradley, Suzanne; Kauffman, Carol; Bedimo, Roger; Crowley, Anna Lisa; Douglas, Pamela; Drew, Laura; Holland, Thomas; Lalani, Tahaniyat; Mudrick, Daniel; Samad, Zaniab; Stryjewski, Martin; Woods, Christopher W.; Lerakis, Stamatios; Cantey, Robert; Steed, Lisa; Wray, Dannah; Dickerman, Stuart A.; Bonilla, Hector; Di Persio, Joseph; Salstrom, Sara Jane; Baddley, John; Patel, Mukesh; Peterson, Gail; Stancoven, Amy; Afonso, Luis; Kulman, Theresa; Levine, Donald; Rybak, Michael; Cabell, Christopher H.; Baloch, Khaula; Dixon, Christy C.; Harding, Tina; Jones-Richmond, Marian; Pappas, Paul; Park, Lawrence P.; Redick, Thomas; Stafford, Judy; Anstrom, Kevin; Bayer, Arnold S.; Karchmer, A. W.; Durack, David T.; Eykyn, Susannah; Moreillon, Phillipe.

In: Clinical Infectious Diseases, Vol. 60, No. 5, 2015, p. 741-749.

Research output: Contribution to journalArticle

Chirouze, C, Alla, F, Fowler, VG, Sexton, DJ, Corey, GR, Chu, VH, Wang, A, Erpelding, ML, Durante-Mangoni, E, Fernández-Hidalgo, N, Giannitsioti, E, Hannan, MM, Lejko-Zupanc, T, Miró, JM, Muñoz, P, Murdoch, DR, Tattevin, P, Tribouilloy, C, Hoen, B, Clara, L, Sanchez, M, Nacinovich, F, Oses, PF, Ronderos, R, Sucari, A, Thierer, J, Casabé, J, Cortes, C, Altclas, J, Kogan, S, Spelman, D, Athan, E, Harris, O, Kennedy, K, Tan, R, Gordon, D, Papanicolas, L, Eisen, D, Grigg, L, Street, A, Korman, T, Kotsanas, D, Dever, R, Konecny, P, Lawrence, R, Rees, D, Ryan, S, Feneley, MP, Harkness, J, Jones, P, Post, J, Reinbott, P, Gattringer, R, Wiesbauer, F, Andrade, AR, De Brito, ACP, Guimarães, AC, Grinberg, M, Mansur, AJ, Siciliano, RF, Strabelli, TMV, Vieira, MLC, De Medeiros Tranchesi, RA, Paiva, MG, Fortes, CQ, De Oliveira Ramos, A, Ferraiuoli, G, Golebiovski, W, Lamas, C, Santos, M, Weksler, C, Karlowsky, JA, Keynan, Y, Morris, AM, Rubinstein, E, Jones, SB, Garcia, P, Cereceda, M, Fica, A, Mella, RM, Barsic, B, Bukovski, S, Krajinovic, V, Pangercic, A, Rudez, I, Vincelj, J, Freiberger, T, Pol, J, Zaloudikova, B, Zainab, A, El Kholy, A, Mishaal, M, Rizk, H, Aissa, N, Alauzet, C, Campagnac, C, Doco-Lecompte, T, Selton-Suty, C, Casalta, JP, Fournier, PE, Habib, G, Raoult, D, Thuny, F, Delahaye, F, Delahaye, A, Vandenesch, F, Donal, E, Donnio, PY, Michelet, C, Revest, M, Violette, J, Chevalier, F, Jeu, A, Rusinaru, DMD, Sorel, C, Bernard, Y, Leroy, J, Plesiat, P, Naber, C, Neuerburg, C, Mazaheri, B, Athanasia, S, Deliolanis, I, Giamarellou, H, Tsaganos, T, Mylona, E, Paniara, O, Papanicolaou, K, Pyros, J, Skoutelis, A, Sharma, G, Francis, J, Nair, L, Thomas, V, Venugopal, K, Hurley, J, Gilon, D, Israel, S, Korem, M, Strahilevitz, J, Casillo, R, Cuccurullo, S, Dialetto, G, Irene, M, Ragone, E, Tripodi, MF, Utili, R, Cecchi, E, De Rosa, F, Forno, D, Imazio, M, Trinchero, R, Tebini, A, Grossi, P, Lattanzio, M, Toniolo, A, Goglio, A, Raglio, A, Ravasio, V, Rizzi, M, Suter, F, Carosi, G, Magri, S, Signorini, L, Baban, T, Kanafani, Z, Kanj, SS, Yasmine, M, Abidin, I, Tamin, SS, Martínez, ER, Nieto, GIS, Van Der Meer, JTM, Chambers, S, Holland, D, Morris, A, Raymond, N, Read, K, Dragulescu, S, Ionac, A, Mornos, C, Butkevich, OM, Chipigina, N, Kirill, O, Vadim, K, Vinogradova, T, Edathodu, J, Halim, M, Lum, LN, Tan, RS, Logar, M, Mueller-Premru, M, Commerford, P, Commerford, A, Deetlefs, E, Hansa, C, Ntsekhe, M, Almela, M, Armero, Y, Azqueta, M, Castañeda, X, Cervera, C, Del Rio, A, Falces, C, Garcia-De-La-Maria, C, Fita, G, Gatell, JM, Marco, F, Mestres, CA, Moreno, A, Ninot, S, Paré, C, Pericas, J, Ramirez, J, Rovira, I, Sitges, M, Anguera, I, Font, B, Guma, JR, Bermejo, J, Bouza, E, Fernández, MAG, Gonzalez-Ramallo, V, Marín, M, Pedromingo, M, Roda, J, Rodríguez-Créixems, M, Solis, J, Almirante, B, Tornos, P, De Alarcón, A, Parra, R, Alestig, E, Johansson, M, Olaison, L, Snygg-Martin, U, Pachirat, O, Pachirat, P, Pussadhamma, B, Senthong, V, Casey, A, Elliott, T, Lambert, P, Watkin, R, Eyton, C, Klein, JL, Bradley, S, Kauffman, C, Bedimo, R, Crowley, AL, Douglas, P, Drew, L, Holland, T, Lalani, T, Mudrick, D, Samad, Z, Stryjewski, M, Woods, CW, Lerakis, S, Cantey, R, Steed, L, Wray, D, Dickerman, SA, Bonilla, H, Di Persio, J, Salstrom, SJ, Baddley, J, Patel, M, Peterson, G, Stancoven, A, Afonso, L, Kulman, T, Levine, D, Rybak, M, Cabell, CH, Baloch, K, Dixon, CC, Harding, T, Jones-Richmond, M, Pappas, P, Park, LP, Redick, T, Stafford, J, Anstrom, K, Bayer, AS, Karchmer, AW, Durack, DT, Eykyn, S & Moreillon, P 2015, 'Impact of early valve surgery on outcome of staphylococcus aureus prosthetic valve infective endocarditis: Analysis in the international collaboration of endocarditis-prospective cohort study', Clinical Infectious Diseases, vol. 60, no. 5, pp. 741-749. https://doi.org/10.1093/cid/ciu871
Chirouze, Catherine ; Alla, François ; Fowler, Vance G. ; Sexton, Daniel J. ; Corey, G. Ralph ; Chu, Vivian H. ; Wang, Andrew ; Erpelding, Marie Line ; Durante-Mangoni, Emanuele ; Fernández-Hidalgo, Nuria ; Giannitsioti, Efthymia ; Hannan, Margaret M. ; Lejko-Zupanc, Tatjana ; Miró, José M. ; Muñoz, Patricia ; Murdoch, David R. ; Tattevin, Pierre ; Tribouilloy, Christophe ; Hoen, Bruno ; Clara, Liliana ; Sanchez, Marisa ; Nacinovich, Francisco ; Oses, Pablo Fernandez ; Ronderos, Ricardo ; Sucari, Adriana ; Thierer, Jorge ; Casabé, José ; Cortes, Claudia ; Altclas, Javier ; Kogan, Silvia ; Spelman, Denis ; Athan, Eugene ; Harris, Owen ; Kennedy, Karina ; Tan, Ren ; Gordon, David ; Papanicolas, Lito ; Eisen, Damon ; Grigg, Leeanne ; Street, Alan ; Korman, Tony ; Kotsanas, Despina ; Dever, Robyn ; Konecny, Pam ; Lawrence, Richard ; Rees, David ; Ryan, Suzanne ; Feneley, Michael P. ; Harkness, John ; Jones, Phillip ; Post, Jeffrey ; Reinbott, Porl ; Gattringer, Rainer ; Wiesbauer, Franz ; Andrade, Adriana Ribas ; De Brito, Ana Cláudia Passos ; Guimarães, Armenio Costa ; Grinberg, Max ; Mansur, Alfredo José ; Siciliano, Rinaldo Focaccia ; Strabelli, Tania Mara Varejao ; Vieira, Marcelo Luiz Campos ; De Medeiros Tranchesi, Regina Aparecida ; Paiva, Marcelo Goulart ; Fortes, Claudio Querido ; De Oliveira Ramos, Auristela ; Ferraiuoli, Giovanna ; Golebiovski, Wilma ; Lamas, Cristiane ; Santos, Marisa ; Weksler, Clara ; Karlowsky, James A. ; Keynan, Yoav ; Morris, Andrew M. ; Rubinstein, Ethan ; Jones, Sandra Braun ; Garcia, Patricia ; Cereceda, M. ; Fica, Alberto ; Mella, Rodrigo Montagna ; Barsic, Bruno ; Bukovski, Suzana ; Krajinovic, Vladimir ; Pangercic, Ana ; Rudez, Igor ; Vincelj, Josip ; Freiberger, Tomas ; Pol, Jiri ; Zaloudikova, Barbora ; Zainab, Ashour ; El Kholy, Amani ; Mishaal, Marwa ; Rizk, Hussien ; Aissa, Neijla ; Alauzet, Corentine ; Campagnac, Catherine ; Doco-Lecompte, Thanh ; Selton-Suty, Christine ; Casalta, Jean Paul ; Fournier, Pierre Edouard ; Habib, Gilbert ; Raoult, Didier ; Thuny, Franck ; Delahaye, François ; Delahaye, Armelle ; Vandenesch, Francois ; Donal, Erwan ; Donnio, Pierre Yves ; Michelet, Christian ; Revest, Matthieu ; Violette, Jérémie ; Chevalier, Florent ; Jeu, Antoine ; Rusinaru, Dan M D ; Sorel, Claire ; Bernard, Yvette ; Leroy, Joel ; Plesiat, Patrick ; Naber, Christoph ; Neuerburg, Carl ; Mazaheri, Bahram ; Athanasia, Sofia ; Deliolanis, Ioannis ; Giamarellou, Helen ; Tsaganos, Thomas ; Mylona, Elena ; Paniara, Olga ; Papanicolaou, Konstantinos ; Pyros, John ; Skoutelis, Athanasios ; Sharma, Gautam ; Francis, Johnson ; Nair, Lathi ; Thomas, Vinod ; Venugopal, Krishnan ; Hurley, John ; Gilon, Dan ; Israel, Sarah ; Korem, Maya ; Strahilevitz, Jacob ; Casillo, Roberta ; Cuccurullo, Susanna ; Dialetto, Giovanni ; Irene, Mattucci ; Ragone, Enrico ; Tripodi, Marie Françoise ; Utili, Riccardo ; Cecchi, Enrico ; De Rosa, Francesco ; Forno, Davide ; Imazio, Massimo ; Trinchero, Rita ; Tebini, Alessandro ; Grossi, Paolo ; Lattanzio, Mariangela ; Toniolo, Antonio ; Goglio, Antonio ; Raglio, Annibale ; Ravasio, Veronica ; Rizzi, Marco ; Suter, Fredy ; Carosi, Giampiero ; Magri, Silvia ; Signorini, Liana ; Baban, Tania ; Kanafani, Zeina ; Kanj, Souha S. ; Yasmine, Mohamad ; Abidin, Imran ; Tamin, Syahidah Syed ; Martínez, Eduardo Rivera ; Nieto, Gabriel Israel Soto ; Van Der Meer, Jan T M ; Chambers, Stephen ; Holland, David ; Morris, Arthur ; Raymond, Nigel ; Read, Kerry ; Dragulescu, Stefan ; Ionac, Adina ; Mornos, Cristian ; Butkevich, O. M. ; Chipigina, Natalia ; Kirill, Ozerecky ; Vadim, Kulichenko ; Vinogradova, Tatiana ; Edathodu, Jameela ; Halim, Magid ; Lum, Luh Nah ; Tan, Ru San ; Logar, Mateja ; Mueller-Premru, Manica ; Commerford, Patrick ; Commerford, Anita ; Deetlefs, Eduan ; Hansa, Cass ; Ntsekhe, Mpiko ; Almela, Manuel ; Armero, Yolanda ; Azqueta, Manuel ; Castañeda, Ximena ; Cervera, Carlos ; Del Rio, Ana ; Falces, Carlos ; Garcia-De-La-Maria, Cristina ; Fita, Guillermina ; Gatell, Jose M. ; Marco, Francesc ; Mestres, Carlos A. ; Moreno, Asuncion ; Ninot, Salvador ; Paré, Carlos ; Pericas, Joan ; Ramirez, Jose ; Rovira, Irene ; Sitges, Marta ; Anguera, Ignasi ; Font, Bernat ; Guma, Joan Raimon ; Bermejo, Javier ; Bouza, Emilio ; Fernández, Miguel Angel Garcia ; Gonzalez-Ramallo, Victor ; Marín, Mercedes ; Pedromingo, Miguel ; Roda, Jorge ; Rodríguez-Créixems, Marta ; Solis, Jorge ; Almirante, Benito ; Tornos, Pilar ; De Alarcón, Arístides ; Parra, Ricardo ; Alestig, Eric ; Johansson, Magnus ; Olaison, Lars ; Snygg-Martin, Ulrika ; Pachirat, Orathai ; Pachirat, Pimchitra ; Pussadhamma, Burabha ; Senthong, Vichai ; Casey, Anna ; Elliott, Tom ; Lambert, Peter ; Watkin, Richard ; Eyton, Christina ; Klein, John L. ; Bradley, Suzanne ; Kauffman, Carol ; Bedimo, Roger ; Crowley, Anna Lisa ; Douglas, Pamela ; Drew, Laura ; Holland, Thomas ; Lalani, Tahaniyat ; Mudrick, Daniel ; Samad, Zaniab ; Stryjewski, Martin ; Woods, Christopher W. ; Lerakis, Stamatios ; Cantey, Robert ; Steed, Lisa ; Wray, Dannah ; Dickerman, Stuart A. ; Bonilla, Hector ; Di Persio, Joseph ; Salstrom, Sara Jane ; Baddley, John ; Patel, Mukesh ; Peterson, Gail ; Stancoven, Amy ; Afonso, Luis ; Kulman, Theresa ; Levine, Donald ; Rybak, Michael ; Cabell, Christopher H. ; Baloch, Khaula ; Dixon, Christy C. ; Harding, Tina ; Jones-Richmond, Marian ; Pappas, Paul ; Park, Lawrence P. ; Redick, Thomas ; Stafford, Judy ; Anstrom, Kevin ; Bayer, Arnold S. ; Karchmer, A. W. ; Durack, David T. ; Eykyn, Susannah ; Moreillon, Phillipe. / Impact of early valve surgery on outcome of staphylococcus aureus prosthetic valve infective endocarditis : Analysis in the international collaboration of endocarditis-prospective cohort study. In: Clinical Infectious Diseases. 2015 ; Vol. 60, No. 5. pp. 741-749.
@article{c05cf672e650498eaf2b1fe5e3cf8f9b,
title = "Impact of early valve surgery on outcome of staphylococcus aureus prosthetic valve infective endocarditis: Analysis in the international collaboration of endocarditis-prospective cohort study",
abstract = "Background. The impact of early valve surgery (EVS) on the outcome of Staphylococcus aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this study was to evaluate the association between EVS, performed within the first 60 days of hospitalization, and outcome of SA PVIE within the International Collaboration on Endocarditis-Prospective Cohort Study. Methods. Participants were enrolled between June 2000 and December 2006. Cox proportional hazards modeling that included surgery as a time-dependent covariate and propensity adjustment for likelihood to receive cardiac surgery was used to evaluate the impact of EVS and 1-year all-cause mortality on patients with definite left-sided S. aureus PVIE and no history of injection drug use. Results. EVS was performed in 74 of the 168 (44.3{\%}) patients. One-year mortality was significantly higher among patients with S. aureus PVIE than in patients with non-S. aureus PVIE (48.2{\%} vs 32.9{\%}; P = .003). Staphylococcus aureus PVIE patients who underwent EVS had a significantly lower 1-year mortality rate (33.8{\%} vs 59.1{\%}; P = .001). In multivariate, propensity-adjusted models, EVS was not associated with 1-year mortality (risk ratio, 0.67 [95{\%} confidence interval, .39-1.15]; P = .15). Conclusions. In this prospective, multinational cohort of patients with S. aureus PVIE, EVS was not associated with reduced 1-year mortality. The decision to pursue EVS should be individualized for each patient, based upon infection-specific characteristics rather than solely upon the microbiology of the infection causing PVIE.",
keywords = "1-year mortality, Endocarditis, Prosthetic valve, Surgery",
author = "Catherine Chirouze and Fran{\cc}ois Alla and Fowler, {Vance G.} and Sexton, {Daniel J.} and Corey, {G. Ralph} and Chu, {Vivian H.} and Andrew Wang and Erpelding, {Marie Line} and Emanuele Durante-Mangoni and Nuria Fern{\'a}ndez-Hidalgo and Efthymia Giannitsioti and Hannan, {Margaret M.} and Tatjana Lejko-Zupanc and Mir{\'o}, {Jos{\'e} M.} and Patricia Mu{\~n}oz and Murdoch, {David R.} and Pierre Tattevin and Christophe Tribouilloy and Bruno Hoen and Liliana Clara and Marisa Sanchez and Francisco Nacinovich and Oses, {Pablo Fernandez} and Ricardo Ronderos and Adriana Sucari and Jorge Thierer and Jos{\'e} Casab{\'e} and Claudia Cortes and Javier Altclas and Silvia Kogan and Denis Spelman and Eugene Athan and Owen Harris and Karina Kennedy and Ren Tan and David Gordon and Lito Papanicolas and Damon Eisen and Leeanne Grigg and Alan Street and Tony Korman and Despina Kotsanas and Robyn Dever and Pam Konecny and Richard Lawrence and David Rees and Suzanne Ryan and Feneley, {Michael P.} and John Harkness and Phillip Jones and Jeffrey Post and Porl Reinbott and Rainer Gattringer and Franz Wiesbauer and Andrade, {Adriana Ribas} and {De Brito}, {Ana Cl{\'a}udia Passos} and Guimar{\~a}es, {Armenio Costa} and Max Grinberg and Mansur, {Alfredo Jos{\'e}} and Siciliano, {Rinaldo Focaccia} and Strabelli, {Tania Mara Varejao} and Vieira, {Marcelo Luiz Campos} and {De Medeiros Tranchesi}, {Regina Aparecida} and Paiva, {Marcelo Goulart} and Fortes, {Claudio Querido} and {De Oliveira Ramos}, Auristela and Giovanna Ferraiuoli and Wilma Golebiovski and Cristiane Lamas and Marisa Santos and Clara Weksler and Karlowsky, {James A.} and Yoav Keynan and Morris, {Andrew M.} and Ethan Rubinstein and Jones, {Sandra Braun} and Patricia Garcia and M. Cereceda and Alberto Fica and Mella, {Rodrigo Montagna} and Bruno Barsic and Suzana Bukovski and Vladimir Krajinovic and Ana Pangercic and Igor Rudez and Josip Vincelj and Tomas Freiberger and Jiri Pol and Barbora Zaloudikova and Ashour Zainab and {El Kholy}, Amani and Marwa Mishaal and Hussien Rizk and Neijla Aissa and Corentine Alauzet and Catherine Campagnac and Thanh Doco-Lecompte and Christine Selton-Suty and Casalta, {Jean Paul} and Fournier, {Pierre Edouard} and Gilbert Habib and Didier Raoult and Franck Thuny and Fran{\cc}ois Delahaye and Armelle Delahaye and Francois Vandenesch and Erwan Donal and Donnio, {Pierre Yves} and Christian Michelet and Matthieu Revest and J{\'e}r{\'e}mie Violette and Florent Chevalier and Antoine Jeu and Rusinaru, {Dan M D} and Claire Sorel and Yvette Bernard and Joel Leroy and Patrick Plesiat and Christoph Naber and Carl Neuerburg and Bahram Mazaheri and Sofia Athanasia and Ioannis Deliolanis and Helen Giamarellou and Thomas Tsaganos and Elena Mylona and Olga Paniara and Konstantinos Papanicolaou and John Pyros and Athanasios Skoutelis and Gautam Sharma and Johnson Francis and Lathi Nair and Vinod Thomas and Krishnan Venugopal and John Hurley and Dan Gilon and Sarah Israel and Maya Korem and Jacob Strahilevitz and Roberta Casillo and Susanna Cuccurullo and Giovanni Dialetto and Mattucci Irene and Enrico Ragone and Tripodi, {Marie Fran{\cc}oise} and Riccardo Utili and Enrico Cecchi and {De Rosa}, Francesco and Davide Forno and Massimo Imazio and Rita Trinchero and Alessandro Tebini and Paolo Grossi and Mariangela Lattanzio and Antonio Toniolo and Antonio Goglio and Annibale Raglio and Veronica Ravasio and Marco Rizzi and Fredy Suter and Giampiero Carosi and Silvia Magri and Liana Signorini and Tania Baban and Zeina Kanafani and Kanj, {Souha S.} and Mohamad Yasmine and Imran Abidin and Tamin, {Syahidah Syed} and Mart{\'i}nez, {Eduardo Rivera} and Nieto, {Gabriel Israel Soto} and {Van Der Meer}, {Jan T M} and Stephen Chambers and David Holland and Arthur Morris and Nigel Raymond and Kerry Read and Stefan Dragulescu and Adina Ionac and Cristian Mornos and Butkevich, {O. M.} and Natalia Chipigina and Ozerecky Kirill and Kulichenko Vadim and Tatiana Vinogradova and Jameela Edathodu and Magid Halim and Lum, {Luh Nah} and Tan, {Ru San} and Mateja Logar and Manica Mueller-Premru and Patrick Commerford and Anita Commerford and Eduan Deetlefs and Cass Hansa and Mpiko Ntsekhe and Manuel Almela and Yolanda Armero and Manuel Azqueta and Ximena Casta{\~n}eda and Carlos Cervera and {Del Rio}, Ana and Carlos Falces and Cristina Garcia-De-La-Maria and Guillermina Fita and Gatell, {Jose M.} and Francesc Marco and Mestres, {Carlos A.} and Asuncion Moreno and Salvador Ninot and Carlos Par{\'e} and Joan Pericas and Jose Ramirez and Irene Rovira and Marta Sitges and Ignasi Anguera and Bernat Font and Guma, {Joan Raimon} and Javier Bermejo and Emilio Bouza and Fern{\'a}ndez, {Miguel Angel Garcia} and Victor Gonzalez-Ramallo and Mercedes Mar{\'i}n and Miguel Pedromingo and Jorge Roda and Marta Rodr{\'i}guez-Cr{\'e}ixems and Jorge Solis and Benito Almirante and Pilar Tornos and {De Alarc{\'o}n}, Ar{\'i}stides and Ricardo Parra and Eric Alestig and Magnus Johansson and Lars Olaison and Ulrika Snygg-Martin and Orathai Pachirat and Pimchitra Pachirat and Burabha Pussadhamma and Vichai Senthong and Anna Casey and Tom Elliott and Peter Lambert and Richard Watkin and Christina Eyton and Klein, {John L.} and Suzanne Bradley and Carol Kauffman and Roger Bedimo and Crowley, {Anna Lisa} and Pamela Douglas and Laura Drew and Thomas Holland and Tahaniyat Lalani and Daniel Mudrick and Zaniab Samad and Martin Stryjewski and Woods, {Christopher W.} and Stamatios Lerakis and Robert Cantey and Lisa Steed and Dannah Wray and Dickerman, {Stuart A.} and Hector Bonilla and {Di Persio}, Joseph and Salstrom, {Sara Jane} and John Baddley and Mukesh Patel and Gail Peterson and Amy Stancoven and Luis Afonso and Theresa Kulman and Donald Levine and Michael Rybak and Cabell, {Christopher H.} and Khaula Baloch and Dixon, {Christy C.} and Tina Harding and Marian Jones-Richmond and Paul Pappas and Park, {Lawrence P.} and Thomas Redick and Judy Stafford and Kevin Anstrom and Bayer, {Arnold S.} and Karchmer, {A. W.} and Durack, {David T.} and Susannah Eykyn and Phillipe Moreillon",
year = "2015",
doi = "10.1093/cid/ciu871",
language = "English (US)",
volume = "60",
pages = "741--749",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "5",

}

TY - JOUR

T1 - Impact of early valve surgery on outcome of staphylococcus aureus prosthetic valve infective endocarditis

T2 - Analysis in the international collaboration of endocarditis-prospective cohort study

AU - Chirouze, Catherine

AU - Alla, François

AU - Fowler, Vance G.

AU - Sexton, Daniel J.

AU - Corey, G. Ralph

AU - Chu, Vivian H.

AU - Wang, Andrew

AU - Erpelding, Marie Line

AU - Durante-Mangoni, Emanuele

AU - Fernández-Hidalgo, Nuria

AU - Giannitsioti, Efthymia

AU - Hannan, Margaret M.

AU - Lejko-Zupanc, Tatjana

AU - Miró, José M.

AU - Muñoz, Patricia

AU - Murdoch, David R.

AU - Tattevin, Pierre

AU - Tribouilloy, Christophe

AU - Hoen, Bruno

AU - Clara, Liliana

AU - Sanchez, Marisa

AU - Nacinovich, Francisco

AU - Oses, Pablo Fernandez

AU - Ronderos, Ricardo

AU - Sucari, Adriana

AU - Thierer, Jorge

AU - Casabé, José

AU - Cortes, Claudia

AU - Altclas, Javier

AU - Kogan, Silvia

AU - Spelman, Denis

AU - Athan, Eugene

AU - Harris, Owen

AU - Kennedy, Karina

AU - Tan, Ren

AU - Gordon, David

AU - Papanicolas, Lito

AU - Eisen, Damon

AU - Grigg, Leeanne

AU - Street, Alan

AU - Korman, Tony

AU - Kotsanas, Despina

AU - Dever, Robyn

AU - Konecny, Pam

AU - Lawrence, Richard

AU - Rees, David

AU - Ryan, Suzanne

AU - Feneley, Michael P.

AU - Harkness, John

AU - Jones, Phillip

AU - Post, Jeffrey

AU - Reinbott, Porl

AU - Gattringer, Rainer

AU - Wiesbauer, Franz

AU - Andrade, Adriana Ribas

AU - De Brito, Ana Cláudia Passos

AU - Guimarães, Armenio Costa

AU - Grinberg, Max

AU - Mansur, Alfredo José

AU - Siciliano, Rinaldo Focaccia

AU - Strabelli, Tania Mara Varejao

AU - Vieira, Marcelo Luiz Campos

AU - De Medeiros Tranchesi, Regina Aparecida

AU - Paiva, Marcelo Goulart

AU - Fortes, Claudio Querido

AU - De Oliveira Ramos, Auristela

AU - Ferraiuoli, Giovanna

AU - Golebiovski, Wilma

AU - Lamas, Cristiane

AU - Santos, Marisa

AU - Weksler, Clara

AU - Karlowsky, James A.

AU - Keynan, Yoav

AU - Morris, Andrew M.

AU - Rubinstein, Ethan

AU - Jones, Sandra Braun

AU - Garcia, Patricia

AU - Cereceda, M.

AU - Fica, Alberto

AU - Mella, Rodrigo Montagna

AU - Barsic, Bruno

AU - Bukovski, Suzana

AU - Krajinovic, Vladimir

AU - Pangercic, Ana

AU - Rudez, Igor

AU - Vincelj, Josip

AU - Freiberger, Tomas

AU - Pol, Jiri

AU - Zaloudikova, Barbora

AU - Zainab, Ashour

AU - El Kholy, Amani

AU - Mishaal, Marwa

AU - Rizk, Hussien

AU - Aissa, Neijla

AU - Alauzet, Corentine

AU - Campagnac, Catherine

AU - Doco-Lecompte, Thanh

AU - Selton-Suty, Christine

AU - Casalta, Jean Paul

AU - Fournier, Pierre Edouard

AU - Habib, Gilbert

AU - Raoult, Didier

AU - Thuny, Franck

AU - Delahaye, François

AU - Delahaye, Armelle

AU - Vandenesch, Francois

AU - Donal, Erwan

AU - Donnio, Pierre Yves

AU - Michelet, Christian

AU - Revest, Matthieu

AU - Violette, Jérémie

AU - Chevalier, Florent

AU - Jeu, Antoine

AU - Rusinaru, Dan M D

AU - Sorel, Claire

AU - Bernard, Yvette

AU - Leroy, Joel

AU - Plesiat, Patrick

AU - Naber, Christoph

AU - Neuerburg, Carl

AU - Mazaheri, Bahram

AU - Athanasia, Sofia

AU - Deliolanis, Ioannis

AU - Giamarellou, Helen

AU - Tsaganos, Thomas

AU - Mylona, Elena

AU - Paniara, Olga

AU - Papanicolaou, Konstantinos

AU - Pyros, John

AU - Skoutelis, Athanasios

AU - Sharma, Gautam

AU - Francis, Johnson

AU - Nair, Lathi

AU - Thomas, Vinod

AU - Venugopal, Krishnan

AU - Hurley, John

AU - Gilon, Dan

AU - Israel, Sarah

AU - Korem, Maya

AU - Strahilevitz, Jacob

AU - Casillo, Roberta

AU - Cuccurullo, Susanna

AU - Dialetto, Giovanni

AU - Irene, Mattucci

AU - Ragone, Enrico

AU - Tripodi, Marie Françoise

AU - Utili, Riccardo

AU - Cecchi, Enrico

AU - De Rosa, Francesco

AU - Forno, Davide

AU - Imazio, Massimo

AU - Trinchero, Rita

AU - Tebini, Alessandro

AU - Grossi, Paolo

AU - Lattanzio, Mariangela

AU - Toniolo, Antonio

AU - Goglio, Antonio

AU - Raglio, Annibale

AU - Ravasio, Veronica

AU - Rizzi, Marco

AU - Suter, Fredy

AU - Carosi, Giampiero

AU - Magri, Silvia

AU - Signorini, Liana

AU - Baban, Tania

AU - Kanafani, Zeina

AU - Kanj, Souha S.

AU - Yasmine, Mohamad

AU - Abidin, Imran

AU - Tamin, Syahidah Syed

AU - Martínez, Eduardo Rivera

AU - Nieto, Gabriel Israel Soto

AU - Van Der Meer, Jan T M

AU - Chambers, Stephen

AU - Holland, David

AU - Morris, Arthur

AU - Raymond, Nigel

AU - Read, Kerry

AU - Dragulescu, Stefan

AU - Ionac, Adina

AU - Mornos, Cristian

AU - Butkevich, O. M.

AU - Chipigina, Natalia

AU - Kirill, Ozerecky

AU - Vadim, Kulichenko

AU - Vinogradova, Tatiana

AU - Edathodu, Jameela

AU - Halim, Magid

AU - Lum, Luh Nah

AU - Tan, Ru San

AU - Logar, Mateja

AU - Mueller-Premru, Manica

AU - Commerford, Patrick

AU - Commerford, Anita

AU - Deetlefs, Eduan

AU - Hansa, Cass

AU - Ntsekhe, Mpiko

AU - Almela, Manuel

AU - Armero, Yolanda

AU - Azqueta, Manuel

AU - Castañeda, Ximena

AU - Cervera, Carlos

AU - Del Rio, Ana

AU - Falces, Carlos

AU - Garcia-De-La-Maria, Cristina

AU - Fita, Guillermina

AU - Gatell, Jose M.

AU - Marco, Francesc

AU - Mestres, Carlos A.

AU - Moreno, Asuncion

AU - Ninot, Salvador

AU - Paré, Carlos

AU - Pericas, Joan

AU - Ramirez, Jose

AU - Rovira, Irene

AU - Sitges, Marta

AU - Anguera, Ignasi

AU - Font, Bernat

AU - Guma, Joan Raimon

AU - Bermejo, Javier

AU - Bouza, Emilio

AU - Fernández, Miguel Angel Garcia

AU - Gonzalez-Ramallo, Victor

AU - Marín, Mercedes

AU - Pedromingo, Miguel

AU - Roda, Jorge

AU - Rodríguez-Créixems, Marta

AU - Solis, Jorge

AU - Almirante, Benito

AU - Tornos, Pilar

AU - De Alarcón, Arístides

AU - Parra, Ricardo

AU - Alestig, Eric

AU - Johansson, Magnus

AU - Olaison, Lars

AU - Snygg-Martin, Ulrika

AU - Pachirat, Orathai

AU - Pachirat, Pimchitra

AU - Pussadhamma, Burabha

AU - Senthong, Vichai

AU - Casey, Anna

AU - Elliott, Tom

AU - Lambert, Peter

AU - Watkin, Richard

AU - Eyton, Christina

AU - Klein, John L.

AU - Bradley, Suzanne

AU - Kauffman, Carol

AU - Bedimo, Roger

AU - Crowley, Anna Lisa

AU - Douglas, Pamela

AU - Drew, Laura

AU - Holland, Thomas

AU - Lalani, Tahaniyat

AU - Mudrick, Daniel

AU - Samad, Zaniab

AU - Stryjewski, Martin

AU - Woods, Christopher W.

AU - Lerakis, Stamatios

AU - Cantey, Robert

AU - Steed, Lisa

AU - Wray, Dannah

AU - Dickerman, Stuart A.

AU - Bonilla, Hector

AU - Di Persio, Joseph

AU - Salstrom, Sara Jane

AU - Baddley, John

AU - Patel, Mukesh

AU - Peterson, Gail

AU - Stancoven, Amy

AU - Afonso, Luis

AU - Kulman, Theresa

AU - Levine, Donald

AU - Rybak, Michael

AU - Cabell, Christopher H.

AU - Baloch, Khaula

AU - Dixon, Christy C.

AU - Harding, Tina

AU - Jones-Richmond, Marian

AU - Pappas, Paul

AU - Park, Lawrence P.

AU - Redick, Thomas

AU - Stafford, Judy

AU - Anstrom, Kevin

AU - Bayer, Arnold S.

AU - Karchmer, A. W.

AU - Durack, David T.

AU - Eykyn, Susannah

AU - Moreillon, Phillipe

PY - 2015

Y1 - 2015

N2 - Background. The impact of early valve surgery (EVS) on the outcome of Staphylococcus aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this study was to evaluate the association between EVS, performed within the first 60 days of hospitalization, and outcome of SA PVIE within the International Collaboration on Endocarditis-Prospective Cohort Study. Methods. Participants were enrolled between June 2000 and December 2006. Cox proportional hazards modeling that included surgery as a time-dependent covariate and propensity adjustment for likelihood to receive cardiac surgery was used to evaluate the impact of EVS and 1-year all-cause mortality on patients with definite left-sided S. aureus PVIE and no history of injection drug use. Results. EVS was performed in 74 of the 168 (44.3%) patients. One-year mortality was significantly higher among patients with S. aureus PVIE than in patients with non-S. aureus PVIE (48.2% vs 32.9%; P = .003). Staphylococcus aureus PVIE patients who underwent EVS had a significantly lower 1-year mortality rate (33.8% vs 59.1%; P = .001). In multivariate, propensity-adjusted models, EVS was not associated with 1-year mortality (risk ratio, 0.67 [95% confidence interval, .39-1.15]; P = .15). Conclusions. In this prospective, multinational cohort of patients with S. aureus PVIE, EVS was not associated with reduced 1-year mortality. The decision to pursue EVS should be individualized for each patient, based upon infection-specific characteristics rather than solely upon the microbiology of the infection causing PVIE.

AB - Background. The impact of early valve surgery (EVS) on the outcome of Staphylococcus aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this study was to evaluate the association between EVS, performed within the first 60 days of hospitalization, and outcome of SA PVIE within the International Collaboration on Endocarditis-Prospective Cohort Study. Methods. Participants were enrolled between June 2000 and December 2006. Cox proportional hazards modeling that included surgery as a time-dependent covariate and propensity adjustment for likelihood to receive cardiac surgery was used to evaluate the impact of EVS and 1-year all-cause mortality on patients with definite left-sided S. aureus PVIE and no history of injection drug use. Results. EVS was performed in 74 of the 168 (44.3%) patients. One-year mortality was significantly higher among patients with S. aureus PVIE than in patients with non-S. aureus PVIE (48.2% vs 32.9%; P = .003). Staphylococcus aureus PVIE patients who underwent EVS had a significantly lower 1-year mortality rate (33.8% vs 59.1%; P = .001). In multivariate, propensity-adjusted models, EVS was not associated with 1-year mortality (risk ratio, 0.67 [95% confidence interval, .39-1.15]; P = .15). Conclusions. In this prospective, multinational cohort of patients with S. aureus PVIE, EVS was not associated with reduced 1-year mortality. The decision to pursue EVS should be individualized for each patient, based upon infection-specific characteristics rather than solely upon the microbiology of the infection causing PVIE.

KW - 1-year mortality

KW - Endocarditis

KW - Prosthetic valve

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=84929147308&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929147308&partnerID=8YFLogxK

U2 - 10.1093/cid/ciu871

DO - 10.1093/cid/ciu871

M3 - Article

VL - 60

SP - 741

EP - 749

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

IS - 5

ER -