Implementation of standardized follow-up care significantly reduces peritonitis in children on chronic peritoneal dialysis

and the SCOPE Collaborative Participants

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The Standardizing Care to improve Outcomes in Pediatric End stage renal disease (SCOPE) Collaborative aims to reduce peritonitis rates in pediatric chronic peritoneal dialysis patients by increasing implementation of standardized care practices. To assess this, monthly care bundle compliance and annualized monthly peritonitis rates were evaluated from 24 SCOPE centers that were participating at collaborative launch and that provided peritonitis rates for the 13 months prior to launch. Changes in bundle compliance were assessed using either a logistic regression model or a generalized linear mixed model. Changes in average annualized peritonitis rates over time were illustrated using the latter model. In the first 36 months of the collaborative, 644 patients with 7977 follow-up encounters were included. The likelihood of compliance with follow-up care practices increased significantly (odds ratio 1.15, 95% confidence interval 1.10, 1.19). Mean monthly peritonitis rates significantly decreased from 0.63 episodes per patient year (95% confidence interval 0.43, 0.92) prelaunch to 0.42 (95% confidence interval 0.31, 0.57) at 36 months postlaunch. A sensitivity analysis confirmed that as mean follow-up compliance increased, peritonitis rates decreased, reaching statistical significance at 80% at which point the prelaunch rate was 42% higher than the rate in the months following achievement of 80% compliance. In its first 3 years, the SCOPE Collaborative has increased the implementation of standardized follow-up care and demonstrated a significant reduction in average monthly peritonitis rates.

Original languageEnglish (US)
Pages (from-to)1346-1354
Number of pages9
JournalKidney International
Volume89
Issue number6
DOIs
StatePublished - 2016

Fingerprint

Aftercare
Peritoneal Dialysis
Peritonitis
Confidence Intervals
Compliance
Patient Care Bundles
Logistic Models
Pediatrics
Chronic Kidney Failure
Linear Models
Odds Ratio

Keywords

  • pediatric nephrology
  • peritoneal dialysis
  • peritonitis

ASJC Scopus subject areas

  • Medicine(all)
  • Nephrology

Cite this

Implementation of standardized follow-up care significantly reduces peritonitis in children on chronic peritoneal dialysis. / and the SCOPE Collaborative Participants.

In: Kidney International, Vol. 89, No. 6, 2016, p. 1346-1354.

Research output: Contribution to journalArticle

@article{7456f7e3970f4fa797e6a5ec439f01e4,
title = "Implementation of standardized follow-up care significantly reduces peritonitis in children on chronic peritoneal dialysis",
abstract = "The Standardizing Care to improve Outcomes in Pediatric End stage renal disease (SCOPE) Collaborative aims to reduce peritonitis rates in pediatric chronic peritoneal dialysis patients by increasing implementation of standardized care practices. To assess this, monthly care bundle compliance and annualized monthly peritonitis rates were evaluated from 24 SCOPE centers that were participating at collaborative launch and that provided peritonitis rates for the 13 months prior to launch. Changes in bundle compliance were assessed using either a logistic regression model or a generalized linear mixed model. Changes in average annualized peritonitis rates over time were illustrated using the latter model. In the first 36 months of the collaborative, 644 patients with 7977 follow-up encounters were included. The likelihood of compliance with follow-up care practices increased significantly (odds ratio 1.15, 95{\%} confidence interval 1.10, 1.19). Mean monthly peritonitis rates significantly decreased from 0.63 episodes per patient year (95{\%} confidence interval 0.43, 0.92) prelaunch to 0.42 (95{\%} confidence interval 0.31, 0.57) at 36 months postlaunch. A sensitivity analysis confirmed that as mean follow-up compliance increased, peritonitis rates decreased, reaching statistical significance at 80{\%} at which point the prelaunch rate was 42{\%} higher than the rate in the months following achievement of 80{\%} compliance. In its first 3 years, the SCOPE Collaborative has increased the implementation of standardized follow-up care and demonstrated a significant reduction in average monthly peritonitis rates.",
keywords = "pediatric nephrology, peritoneal dialysis, peritonitis",
author = "{and the SCOPE Collaborative Participants} and Neu, {Alicia M.} and Troy Richardson and John Lawlor and Jayne Stuart and Jason Newland and Nancy McAfee and Warady, {Bradley A.} and Joshua Zaristky and Susan Kieffner and {Redpath Mahon}, Allison and Dawn Foster and Mahima Keswani and Nancy Majkowski and Richard Blaszak and Christine Blaszak and Michael Somers and Theresa Pak and Diego Aviles and Evie Jenkins and Rachel Lestz and Alice Sanchez and Cynthia Pan and Jackie Dake and Raymond Quigley and Bradley Warady and Grimes, {Jo Lyn} and Kirtida Mistry and Jennifer Carver and {Van De Voorde}, Rene and Ellen Irvin and Samhar Al-Akash and Britt Stone and Guillermo Hidalgo and Malinda Harrington and Alicia Neu and Barbara Case and Sushil Gupta and Andrea Baker and Jack Weaver and Annabelle Chua and Cynthia Wong and Brandy Begin and Isidro Salusky and Barbara Gales and Hiren Patel and Beth Smith and Mark Joseph and Deb Haskins and David Kenagy and Beth Vogt",
year = "2016",
doi = "10.1016/j.kint.2016.02.015",
language = "English (US)",
volume = "89",
pages = "1346--1354",
journal = "Kidney International",
issn = "0085-2538",
publisher = "Nature Publishing Group",
number = "6",

}

TY - JOUR

T1 - Implementation of standardized follow-up care significantly reduces peritonitis in children on chronic peritoneal dialysis

AU - and the SCOPE Collaborative Participants

AU - Neu, Alicia M.

AU - Richardson, Troy

AU - Lawlor, John

AU - Stuart, Jayne

AU - Newland, Jason

AU - McAfee, Nancy

AU - Warady, Bradley A.

AU - Zaristky, Joshua

AU - Kieffner, Susan

AU - Redpath Mahon, Allison

AU - Foster, Dawn

AU - Keswani, Mahima

AU - Majkowski, Nancy

AU - Blaszak, Richard

AU - Blaszak, Christine

AU - Somers, Michael

AU - Pak, Theresa

AU - Aviles, Diego

AU - Jenkins, Evie

AU - Lestz, Rachel

AU - Sanchez, Alice

AU - Pan, Cynthia

AU - Dake, Jackie

AU - Quigley, Raymond

AU - Warady, Bradley

AU - Grimes, Jo Lyn

AU - Mistry, Kirtida

AU - Carver, Jennifer

AU - Van De Voorde, Rene

AU - Irvin, Ellen

AU - Al-Akash, Samhar

AU - Stone, Britt

AU - Hidalgo, Guillermo

AU - Harrington, Malinda

AU - Neu, Alicia

AU - Case, Barbara

AU - Gupta, Sushil

AU - Baker, Andrea

AU - Weaver, Jack

AU - Chua, Annabelle

AU - Wong, Cynthia

AU - Begin, Brandy

AU - Salusky, Isidro

AU - Gales, Barbara

AU - Patel, Hiren

AU - Smith, Beth

AU - Joseph, Mark

AU - Haskins, Deb

AU - Kenagy, David

AU - Vogt, Beth

PY - 2016

Y1 - 2016

N2 - The Standardizing Care to improve Outcomes in Pediatric End stage renal disease (SCOPE) Collaborative aims to reduce peritonitis rates in pediatric chronic peritoneal dialysis patients by increasing implementation of standardized care practices. To assess this, monthly care bundle compliance and annualized monthly peritonitis rates were evaluated from 24 SCOPE centers that were participating at collaborative launch and that provided peritonitis rates for the 13 months prior to launch. Changes in bundle compliance were assessed using either a logistic regression model or a generalized linear mixed model. Changes in average annualized peritonitis rates over time were illustrated using the latter model. In the first 36 months of the collaborative, 644 patients with 7977 follow-up encounters were included. The likelihood of compliance with follow-up care practices increased significantly (odds ratio 1.15, 95% confidence interval 1.10, 1.19). Mean monthly peritonitis rates significantly decreased from 0.63 episodes per patient year (95% confidence interval 0.43, 0.92) prelaunch to 0.42 (95% confidence interval 0.31, 0.57) at 36 months postlaunch. A sensitivity analysis confirmed that as mean follow-up compliance increased, peritonitis rates decreased, reaching statistical significance at 80% at which point the prelaunch rate was 42% higher than the rate in the months following achievement of 80% compliance. In its first 3 years, the SCOPE Collaborative has increased the implementation of standardized follow-up care and demonstrated a significant reduction in average monthly peritonitis rates.

AB - The Standardizing Care to improve Outcomes in Pediatric End stage renal disease (SCOPE) Collaborative aims to reduce peritonitis rates in pediatric chronic peritoneal dialysis patients by increasing implementation of standardized care practices. To assess this, monthly care bundle compliance and annualized monthly peritonitis rates were evaluated from 24 SCOPE centers that were participating at collaborative launch and that provided peritonitis rates for the 13 months prior to launch. Changes in bundle compliance were assessed using either a logistic regression model or a generalized linear mixed model. Changes in average annualized peritonitis rates over time were illustrated using the latter model. In the first 36 months of the collaborative, 644 patients with 7977 follow-up encounters were included. The likelihood of compliance with follow-up care practices increased significantly (odds ratio 1.15, 95% confidence interval 1.10, 1.19). Mean monthly peritonitis rates significantly decreased from 0.63 episodes per patient year (95% confidence interval 0.43, 0.92) prelaunch to 0.42 (95% confidence interval 0.31, 0.57) at 36 months postlaunch. A sensitivity analysis confirmed that as mean follow-up compliance increased, peritonitis rates decreased, reaching statistical significance at 80% at which point the prelaunch rate was 42% higher than the rate in the months following achievement of 80% compliance. In its first 3 years, the SCOPE Collaborative has increased the implementation of standardized follow-up care and demonstrated a significant reduction in average monthly peritonitis rates.

KW - pediatric nephrology

KW - peritoneal dialysis

KW - peritonitis

UR - http://www.scopus.com/inward/record.url?scp=84978062878&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84978062878&partnerID=8YFLogxK

U2 - 10.1016/j.kint.2016.02.015

DO - 10.1016/j.kint.2016.02.015

M3 - Article

C2 - 27165827

AN - SCOPUS:84978062878

VL - 89

SP - 1346

EP - 1354

JO - Kidney International

JF - Kidney International

SN - 0085-2538

IS - 6

ER -