Implementing large-scale ENU mutagenesis screens in North America

Amander T. Clark; Daniel Goldowitz; Joseph S. Takahashi; Martha Hotz Vitaterna; Sandra M. Siepka; Luanne L. Peters; Wayne N. Frankel; George A. Carlson; Janet Rossant; Joseph H. Nadeau; Monica J. Justice

doi:10.1007/s10709-004-1436-6

Implementing large-scale ENU mutagenesis screens in North America

Amander T. Clark, Daniel Goldowitz, Joseph S. Takahashi, Martha Hotz Vitaterna, Sandra M. Siepka, Luanne L. Peters, Wayne N. Frankel, George A. Carlson, Janet Rossant, Joseph H. Nadeau, Monica J. Justice

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Abstract

A step towards annotating the mouse genome is to use forward genetics in phenotype-driven screens to saturate the genome with mutations. The purpose of this article is to highlight the new projects in North America that are focused on isolating mouse mutations after ENU mutagenesis and phenotype screening.

Original language	English (US)
Pages (from-to)	51-64
Number of pages	14
Journal	Genetica
Volume	122
Issue number	1
DOIs	https://doi.org/10.1007/s10709-004-1436-6
State	Published - Sep 2004

Keywords

Human Genome Project
Mouse Genome Project
balancer chromosomes
mouse mutagenesis
phenotype screens

ASJC Scopus subject areas

Animal Science and Zoology
Genetics
Plant Science
Insect Science

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10.1007/s10709-004-1436-6

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title = "Implementing large-scale ENU mutagenesis screens in North America",

abstract = "A step towards annotating the mouse genome is to use forward genetics in phenotype-driven screens to saturate the genome with mutations. The purpose of this article is to highlight the new projects in North America that are focused on isolating mouse mutations after ENU mutagenesis and phenotype screening.",

keywords = "Human Genome Project, Mouse Genome Project, balancer chromosomes, mouse mutagenesis, phenotype screens",

author = "Clark, {Amander T.} and Daniel Goldowitz and Takahashi, {Joseph S.} and Vitaterna, {Martha Hotz} and Siepka, {Sandra M.} and Peters, {Luanne L.} and Frankel, {Wayne N.} and Carlson, {George A.} and Janet Rossant and Nadeau, {Joseph H.} and Justice, {Monica J.}",

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doi = "10.1007/s10709-004-1436-6",

language = "English (US)",

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AU - Clark, Amander T.

AU - Goldowitz, Daniel

AU - Takahashi, Joseph S.

AU - Vitaterna, Martha Hotz

AU - Siepka, Sandra M.

AU - Peters, Luanne L.

AU - Frankel, Wayne N.

AU - Carlson, George A.

AU - Rossant, Janet

AU - Nadeau, Joseph H.

AU - Justice, Monica J.

PY - 2004/9

Y1 - 2004/9

N2 - A step towards annotating the mouse genome is to use forward genetics in phenotype-driven screens to saturate the genome with mutations. The purpose of this article is to highlight the new projects in North America that are focused on isolating mouse mutations after ENU mutagenesis and phenotype screening.

AB - A step towards annotating the mouse genome is to use forward genetics in phenotype-driven screens to saturate the genome with mutations. The purpose of this article is to highlight the new projects in North America that are focused on isolating mouse mutations after ENU mutagenesis and phenotype screening.

KW - Human Genome Project

KW - Mouse Genome Project

KW - balancer chromosomes

KW - mouse mutagenesis

KW - phenotype screens

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Implementing large-scale ENU mutagenesis screens in North America

Abstract

Keywords

ASJC Scopus subject areas

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