Improved Diagnostic Sensitivity of Bowel Disease of Prematurity on Contrast-Enhanced Ultrasound

Jamaal L. Benjamin; Rebecca Dennis; Stacy White; David Munson; Sudha A. Anupindi; Maciej Piskunowicz; Kassa Darge; Ami Gokli; Misun Hwang

doi:10.1002/jum.15168

Improved Diagnostic Sensitivity of Bowel Disease of Prematurity on Contrast-Enhanced Ultrasound

Jamaal L. Benjamin, Rebecca Dennis, Stacy White, David Munson, Sudha A. Anupindi, Maciej Piskunowicz, Kassa Darge, Ami Gokli, Misun Hwang

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Bowel diseases of prematurity, including necrotizing enterocolitis, are dreaded ailments of neonates. Early diagnosis is difficult, with clinical and radiographic findings often inconclusive. We present a novel use of contrast-enhanced ultrasound in detection of pediatric bowel disease. Early identification of compromised blood flow or an at-risk bowel can be quantitatively detected and monitored. This ability has implications for guidance of emerging therapies, allowing targeting of inflammation. These findings represent an advancement in detection of bowel disease in neonates.

Original language	English (US)
Pages (from-to)	1031-1036
Number of pages	6
Journal	Journal of Ultrasound in Medicine
Volume	39
Issue number	5
DOIs	https://doi.org/10.1002/jum.15168
State	Published - May 1 2020
Externally published	Yes

Keywords

bowel disease of prematurity
contrast-enhanced ultrasound
necrotizing enterocolitis
neonate

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

Access to Document

10.1002/jum.15168

Cite this

@article{f96f6d08d1e84e67a0e8135bbe64251c,

title = "Improved Diagnostic Sensitivity of Bowel Disease of Prematurity on Contrast-Enhanced Ultrasound",

abstract = "Bowel diseases of prematurity, including necrotizing enterocolitis, are dreaded ailments of neonates. Early diagnosis is difficult, with clinical and radiographic findings often inconclusive. We present a novel use of contrast-enhanced ultrasound in detection of pediatric bowel disease. Early identification of compromised blood flow or an at-risk bowel can be quantitatively detected and monitored. This ability has implications for guidance of emerging therapies, allowing targeting of inflammation. These findings represent an advancement in detection of bowel disease in neonates.",

keywords = "bowel disease of prematurity, contrast-enhanced ultrasound, necrotizing enterocolitis, neonate",

author = "Benjamin, {Jamaal L.} and Rebecca Dennis and Stacy White and David Munson and Anupindi, {Sudha A.} and Maciej Piskunowicz and Kassa Darge and Ami Gokli and Misun Hwang",

note = "Publisher Copyright: {\textcopyright} 2019 by the American Institute of Ultrasound in Medicine",

year = "2020",

month = may,

day = "1",

doi = "10.1002/jum.15168",

language = "English (US)",

volume = "39",

pages = "1031--1036",

journal = "Journal of Ultrasound in Medicine",

issn = "0278-4297",

publisher = "American Institute of Ultrasound in Medicine",

number = "5",

}

TY - JOUR

T1 - Improved Diagnostic Sensitivity of Bowel Disease of Prematurity on Contrast-Enhanced Ultrasound

AU - Benjamin, Jamaal L.

AU - Dennis, Rebecca

AU - White, Stacy

AU - Munson, David

AU - Anupindi, Sudha A.

AU - Piskunowicz, Maciej

AU - Darge, Kassa

AU - Gokli, Ami

AU - Hwang, Misun

PY - 2020/5/1

Y1 - 2020/5/1

N2 - Bowel diseases of prematurity, including necrotizing enterocolitis, are dreaded ailments of neonates. Early diagnosis is difficult, with clinical and radiographic findings often inconclusive. We present a novel use of contrast-enhanced ultrasound in detection of pediatric bowel disease. Early identification of compromised blood flow or an at-risk bowel can be quantitatively detected and monitored. This ability has implications for guidance of emerging therapies, allowing targeting of inflammation. These findings represent an advancement in detection of bowel disease in neonates.

AB - Bowel diseases of prematurity, including necrotizing enterocolitis, are dreaded ailments of neonates. Early diagnosis is difficult, with clinical and radiographic findings often inconclusive. We present a novel use of contrast-enhanced ultrasound in detection of pediatric bowel disease. Early identification of compromised blood flow or an at-risk bowel can be quantitatively detected and monitored. This ability has implications for guidance of emerging therapies, allowing targeting of inflammation. These findings represent an advancement in detection of bowel disease in neonates.

KW - bowel disease of prematurity

KW - contrast-enhanced ultrasound

KW - necrotizing enterocolitis

KW - neonate

UR - http://www.scopus.com/inward/record.url?scp=85083911294&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85083911294&partnerID=8YFLogxK

U2 - 10.1002/jum.15168

DO - 10.1002/jum.15168

M3 - Article

C2 - 31705672

AN - SCOPUS:85083911294

SN - 0278-4297

VL - 39

SP - 1031

EP - 1036

JO - Journal of Ultrasound in Medicine

JF - Journal of Ultrasound in Medicine

IS - 5

ER -

Improved Diagnostic Sensitivity of Bowel Disease of Prematurity on Contrast-Enhanced Ultrasound

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this