Improvement in regional cerebral blood flow and cerebral vasoreactivity after extracranial-intracranial arterial bypass

H. H. Batjer, M. D. Devous, P. D. Purdy, B. Mickey, F. J. Bonte, D. Samson, R. C. Heros, F. G. Diaz, J. I. Ausman

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Regional cerebral blood flow was measured with xenon-133 inhalation single photon emission computed tomography in a patient who developed a neurological deficit after carotid ligation. Hemispheric hypoperfusion was noted in resting studies and impaired vasoreactivity was suggested by lack of symmetrical flow augmentation after acetazolamide administration. Because of progressive neurological deterioration, an extracranial-intracranial bypass was performed. After prompt neurological improvement, repeat cerebral blood flow measurements at 1 and 9 weeks postoperatively confirmed improvement in resting flow and vasoreactivity. It is possible that decreased cerebrovascular reserve implied by measurements of vasoreactivity can identify patients who will benefit from surgical revascularization.

Original languageEnglish (US)
Pages (from-to)913-919
Number of pages7
JournalNeurosurgery
Volume22
Issue number5
DOIs
StatePublished - May 1988

Keywords

  • Cerebral blood flow
  • Cerebral ischemia
  • Revascularization

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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