Improvement of oral colonic lavage with supplemental simethicone

William A. Shaver, Patrick Storms, Walter L. Peterson

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


We have noted that colons of patients prepared for colonoscopy with Golytely, a nonabsorbable electrolyte lavage solution, frequently contain foam which may obscure small mucosal lesions. Therefore, a randomized, blinded controlled trial was performed to determine the prevalence of Golytely-induced foam and the effect of supplemental simethicone in decreasing the prevalence of foam. Foam was present in 32% of colons prepared with Golytely alone but in none of the colons prepared with Golytely supplemented with simethicone. In addition, only 5% of colons prepared with supplemental simethicone had residual stool noted at the time of colonoscopy, a significant improvement over the 39% prevalence of residual stool in colons prepared with Golytely alone. Addition of simethicone to Golytely lavage decreases the prevalence of colonic foam and residual stool.

Original languageEnglish (US)
Pages (from-to)185-188
Number of pages4
JournalDigestive Diseases and Sciences
Issue number2
StatePublished - Feb 1 1988


  • colonic lavage
  • colonoscopy
  • simethicone

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology


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