In vivo comparison of fourier-domain optical coherence tomography and intravascular ultrasonography

Sathyadeepak Ramesh, Aristotelis Papayannis, Abdul Rahman Abdel-Karim, Subhash Banerjee, Emmanouil Brilakis

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4 Scopus citations

Abstract

BACKGROUND: We sought to evaluate the findings of Fourier-domain optical coherence tomography (FD-OCT) and intravascular ultrasonography (IVUS) used for the in vivo assessment of coronary lesions. METHODS: We identified 19 lesions in 15 patients undergoing percutaneous coronary intervention that were assessed by both FD-OCT and IVUS and compared the lumen area and maximum/minimum lumen diameter at the site of maximum stenosis and the proximal and distal reference cross-sections. RESULTS: At the site of maximum stenosis, excellent correlation was found between FD-OCT and IVUS measurements: minimum lumen area (3.80 ± 2.36 mm 2 and 4.60 ± 2.13 mm 2, respectively; P=.002; Spearman's = 0.94), maximum lumen diameter (2.30 ± 0.79 mm 2 and 2.54 ± 0.60 mm 2, respectively; P=.005; Spearman's = 0.93), and minimum lumen diameter (1.89 ± 0.69 mm 2 and 2.24 ± 0.54 mm 2, respectively; P=.0001; Spearman's = 0.90). Weaker correlations were found between FD-OCT and IVUS measurements of the proximal reference lumen area (4.74 ± 1.86 mm 2 and 5.16 ± 2.10 mm 2, respectively; P=.33; Spearman's = 0.76) and distal reference lumen area (5.14 ± 1.60 mm 2 and 5.47 ± 2.45 mm 2, respectively; P=.144; Spearman's = 0.72). CONCLUSIONS: Excellent correlation was found in FD-OCT and IVUS luminal measurements at the site of maximum coronary stenosis with weaker correlation at the proximal and distal reference cross-sections. FD-OCT minimum lumen area measurements were smaller than the IVUS measurements.

Original languageEnglish (US)
Pages (from-to)111-115
Number of pages5
JournalJournal of Invasive Cardiology
Volume24
Issue number3
Publication statusPublished - Mar 2012

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Keywords

  • coronary angiography
  • intravascular ultrasonography
  • optical coherence tomography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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