In vivo measurement of myocardial mass using nuclear magnetic resonance imaging

A. M. Keller, Ronald M Peshock, Craig R Malloy, L. M. Buja, R. Nunnally, R. W. Parkey, J. T. Willerson

Research output: Contribution to journalArticlepeer-review

117 Scopus citations

Abstract

To examine the accuracy of nuclear magnetic resonance imaging in measuring left ventricular mass, measurements of left ventricular mass made using this technique were compared with left ventricular weight in 10 mongrel dogs. Left ventricular myocardial volume was measured from five short-axis ehd-diastolic images that spanned the left ventricle. Left ventricular mass was calculated from left ventricular myocardial volume and compared with the left ventricular weight determined after formalin immersion-fixation. Linear regression analysis yielded the following relation in grams: left ventricular mass determined using nuclear magnetic resonance imaging = (0.94) (left ventricular weight) + 9.1 (r = 0.98, SEE = 6.1 g). The small overestimation of left ventricular weight by nuclear magnetic resonance imaging was judged to be secondary to both difficulty with proper border definition and partial volume effects. Hence, this imaging technique can be used to obtain accurate measurements of left ventricular mass in dogs in vivo.

Original languageEnglish (US)
Pages (from-to)113-117
Number of pages5
JournalJournal of the American College of Cardiology
Volume8
Issue number1
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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