In vivo three-dimensional photoacoustic tomography of a whole mouse head

Kwang Hyun Song, George Stoica, Lihong V. Wang

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

An in vivo photoacoustic imaging system was designed and implemented to image the entire small animal head. A special scanning gantry was designed to enable in vivo imaging in coronal cross sections with high contrast and good spatial resolution for the first time to our knowledge. By use of a 2.25 MHz ultrasonic transducer with a 6 mm diameter active element, an in-plane radial resolution of ∼312 μm was achieved. Deeply seated arterial and venous vessels in the head measuring up to 1.7 cm in diameter were simultaneously imaged in vivo with 804 nm wavelength laser excitation of photoacoustic waves.

Original languageEnglish (US)
Pages (from-to)2453-2455
Number of pages3
JournalOptics Letters
Volume31
Issue number16
DOIs
StatePublished - Aug 15 2006

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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