In vivo three-dimensional photoacoustic tomography of a whole mouse head

Kwang Hyun Song, George Stoica, Lihong V. Wang

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

An in vivo photoacoustic imaging system was designed and implemented to image the entire small animal head. A special scanning gantry was designed to enable in vivo imaging in coronal cross sections with high contrast and good spatial resolution for the first time to our knowledge. By use of a 2.25 MHz ultrasonic transducer with a 6 mm diameter active element, an in-plane radial resolution of ∼312 μm was achieved. Deeply seated arterial and venous vessels in the head measuring up to 1.7 cm in diameter were simultaneously imaged in vivo with 804 nm wavelength laser excitation of photoacoustic waves.

Original languageEnglish (US)
Pages (from-to)2453-2455
Number of pages3
JournalOptics Letters
Volume31
Issue number16
DOIs
StatePublished - Aug 15 2006

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mice
tomography
gantry cranes
vessels
animals
transducers
ultrasonics
spatial resolution
scanning
cross sections
wavelengths
excitation
lasers

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

In vivo three-dimensional photoacoustic tomography of a whole mouse head. / Song, Kwang Hyun; Stoica, George; Wang, Lihong V.

In: Optics Letters, Vol. 31, No. 16, 15.08.2006, p. 2453-2455.

Research output: Contribution to journalArticle

Song, Kwang Hyun ; Stoica, George ; Wang, Lihong V. / In vivo three-dimensional photoacoustic tomography of a whole mouse head. In: Optics Letters. 2006 ; Vol. 31, No. 16. pp. 2453-2455.
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