Purpose: We investigated in a prospective study the incidence of congestive heart failure (CHF) in older persons with and without diabetes mellitus. Methods: In a prospective study of 865 men and 1,872 women, mean age 81 ± 9 years (range 60 to 103), 690 persons (25%) had diabetes mellitus. These 2,737 persons were followed for the incidence of new CHF. Results: New CHF developed in 739 of 2,737 persons (27%). Follow-up was 39±22 months for diabetics versus 44±25 months for nondiabetics (p=0.0001). Cox regression analysis showed that age (p=0.0001, risk ratio = 1.048), hypertension (p=0.0001, risk ratio = 2.524), coronary artery disease (CAD) (p=0.0001, risk ratio = 4.008), male gender (p=0.0001, risk ratio = 1.399), and diabetes mellitus (p=0.0003, risk ratio = 1.337) were significantly positively associated with the time to the development of CHF. Conclusions: Age, hypertension, CAD, male gender, and diabetes mellitus are significant independent risk factors for the development of CHF in older persons. Clinical Implications: Older persons, men, and persons with hypertension, CAD, or diabetes mellitus are more likely to develop CHF.
|Original language||English (US)|
|Issue number||4 SUPPL.|
|State||Published - Oct 1 1998|
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Critical Care and Intensive Care Medicine
- Cardiology and Cardiovascular Medicine