Incidence of heart failure in 2,737 older persons with and without diabetes mellitus

Wilbert S. Aronow, Ahn Chul

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

Study objectives: To investigate in older persons whether diabetes mellitus is an independent risk factor for congestive heart failure (CHF). Design: A prospective study was performed in 2,737 older persons investigating the incidence of new CHF in persons with and without diabetes mellitus. Setting: A long-term health-care facility. Patients: Eight hundred sixty-five men and 1,872 women, with a mean age of 81 ± 9 years. Measurements and results: At 43-month follow-up, new CHF developed in 272 of 690 persons (39%) with diabetes mellitus and in 467 of 2,047 persons (23%) without diabetes mellitus (p < 0.0001). Cox regression analysis showed that age (p = 0.0001, risk ratio = 1.048), hypertension (p = 0.0001, risk ratio = 2.524), coronary artery disease (p = 0.0001, risk ratio = 4.008), male gender (p = 0.0001, risk ratio = 1.399), and diabetes mellitus (p = 0.0003, risk ratio = 1.337) were significantly positively associated with the time to the development of CHF. Conclusions: Older persons with diabetes mellitus had a 1.3 times higher chance of developing CHF than those without diabetes mellitus after controlling the confounding effects of other prognostic variables.

Original languageEnglish (US)
Pages (from-to)867-868
Number of pages2
JournalChest
Volume115
Issue number3
DOIs
StatePublished - 1999

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Diabetes Mellitus
Heart Failure
Incidence
Odds Ratio
Health Facilities
Long-Term Care
Coronary Artery Disease
Regression Analysis
Prospective Studies
Hypertension
Delivery of Health Care

Keywords

  • Congestive heart failure
  • Coronary artery disease
  • Diabetes mellitus
  • Hypertension
  • Male gender

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Incidence of heart failure in 2,737 older persons with and without diabetes mellitus. / Aronow, Wilbert S.; Chul, Ahn.

In: Chest, Vol. 115, No. 3, 1999, p. 867-868.

Research output: Contribution to journalArticle

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abstract = "Study objectives: To investigate in older persons whether diabetes mellitus is an independent risk factor for congestive heart failure (CHF). Design: A prospective study was performed in 2,737 older persons investigating the incidence of new CHF in persons with and without diabetes mellitus. Setting: A long-term health-care facility. Patients: Eight hundred sixty-five men and 1,872 women, with a mean age of 81 ± 9 years. Measurements and results: At 43-month follow-up, new CHF developed in 272 of 690 persons (39{\%}) with diabetes mellitus and in 467 of 2,047 persons (23{\%}) without diabetes mellitus (p < 0.0001). Cox regression analysis showed that age (p = 0.0001, risk ratio = 1.048), hypertension (p = 0.0001, risk ratio = 2.524), coronary artery disease (p = 0.0001, risk ratio = 4.008), male gender (p = 0.0001, risk ratio = 1.399), and diabetes mellitus (p = 0.0003, risk ratio = 1.337) were significantly positively associated with the time to the development of CHF. Conclusions: Older persons with diabetes mellitus had a 1.3 times higher chance of developing CHF than those without diabetes mellitus after controlling the confounding effects of other prognostic variables.",
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