Abstract
Study objectives: To investigate in older persons whether diabetes mellitus is an independent risk factor for congestive heart failure (CHF). Design: A prospective study was performed in 2,737 older persons investigating the incidence of new CHF in persons with and without diabetes mellitus. Setting: A long-term health-care facility. Patients: Eight hundred sixty-five men and 1,872 women, with a mean age of 81 ± 9 years. Measurements and results: At 43-month follow-up, new CHF developed in 272 of 690 persons (39%) with diabetes mellitus and in 467 of 2,047 persons (23%) without diabetes mellitus (p < 0.0001). Cox regression analysis showed that age (p = 0.0001, risk ratio = 1.048), hypertension (p = 0.0001, risk ratio = 2.524), coronary artery disease (p = 0.0001, risk ratio = 4.008), male gender (p = 0.0001, risk ratio = 1.399), and diabetes mellitus (p = 0.0003, risk ratio = 1.337) were significantly positively associated with the time to the development of CHF. Conclusions: Older persons with diabetes mellitus had a 1.3 times higher chance of developing CHF than those without diabetes mellitus after controlling the confounding effects of other prognostic variables.
Original language | English (US) |
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Pages (from-to) | 867-868 |
Number of pages | 2 |
Journal | CHEST |
Volume | 115 |
Issue number | 3 |
DOIs | |
State | Published - Jan 1 1999 |
Keywords
- Congestive heart failure
- Coronary artery disease
- Diabetes mellitus
- Hypertension
- Male gender
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Critical Care and Intensive Care Medicine
- Cardiology and Cardiovascular Medicine