Incidence of myocardial infarction or stroke or death at 47-month follow-up in patients with diabetes and a predicted exercise capacity ≤85% vs >85% during an exercise treadmill sestamibi stress test

Bredy Pierre-Louis, Wilbert S. Aronow, Joo H. Yoon, Chul Ahn, Albert J. DeLuca, Melvin B. Weiss, Kumar Kalapatapu, Anthony L. Pucillo, Craig E. Monsen

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Abstract

A treadmill exercise sestamibi stress test (TESST) was performed in 609 consecutive diabetic persons with a mean age of 70 years and no history of coronary artery disease (CAD) who were referred for a TESST because of chest pain or dyspnea. Of 609 patients, 301 (49%) had a predicted exercise capacity ≤85% (group A) and 308 (51%) had a predicted exercise capacity >85% (group B). Group A patients had a higher prevalence of myocardial ischemia (43% vs 30%, . P=.0005), 2- or 3-vessel obstructive CAD (38% vs 18%, . P=.001), myocardial infarction (17% vs 9%, . P=.004), death (10% vs 4%, . P=.008), and myocardial infarction or stroke or death at 47-month follow-up (21% vs 12%, . P=.001). Stepwise Cox regression analysis showed that the only significant independent predictor for the time to development of myocardial infarction or stroke or death was a predicted exercise capacity >85% (hazard ratio, 0.52; 95% confidence interval, 0.34-0.78; . P=.002). Diabetic persons with a predicted exercise capacity >85% had a 48% lower chance of myocardial infarction, stroke, or death than those with a predicted exercise capacity ≤85%.

Original languageEnglish (US)
Pages (from-to)14-17
Number of pages4
JournalPreventive Cardiology
Volume13
Issue number1
DOIs
Publication statusPublished - Jan 2010

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Public Health, Environmental and Occupational Health

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