TY - JOUR
T1 - Incidence of myocardial infarction or stroke or death at 47-month follow-up in patients with diabetes and a predicted exercise capacity ≤85% vs >85% during an exercise treadmill sestamibi stress test
AU - Pierre-Louis, Bredy
AU - Aronow, Wilbert S.
AU - Yoon, Joo H.
AU - Ahn, Chul
AU - DeLuca, Albert J.
AU - Weiss, Melvin B.
AU - Kalapatapu, Kumar
AU - Pucillo, Anthony L.
AU - Monsen, Craig E.
PY - 2010/1
Y1 - 2010/1
N2 - A treadmill exercise sestamibi stress test (TESST) was performed in 609 consecutive diabetic persons with a mean age of 70 years and no history of coronary artery disease (CAD) who were referred for a TESST because of chest pain or dyspnea. Of 609 patients, 301 (49%) had a predicted exercise capacity ≤85% (group A) and 308 (51%) had a predicted exercise capacity >85% (group B). Group A patients had a higher prevalence of myocardial ischemia (43% vs 30%, . P=.0005), 2- or 3-vessel obstructive CAD (38% vs 18%, . P=.001), myocardial infarction (17% vs 9%, . P=.004), death (10% vs 4%, . P=.008), and myocardial infarction or stroke or death at 47-month follow-up (21% vs 12%, . P=.001). Stepwise Cox regression analysis showed that the only significant independent predictor for the time to development of myocardial infarction or stroke or death was a predicted exercise capacity >85% (hazard ratio, 0.52; 95% confidence interval, 0.34-0.78; . P=.002). Diabetic persons with a predicted exercise capacity >85% had a 48% lower chance of myocardial infarction, stroke, or death than those with a predicted exercise capacity ≤85%.
AB - A treadmill exercise sestamibi stress test (TESST) was performed in 609 consecutive diabetic persons with a mean age of 70 years and no history of coronary artery disease (CAD) who were referred for a TESST because of chest pain or dyspnea. Of 609 patients, 301 (49%) had a predicted exercise capacity ≤85% (group A) and 308 (51%) had a predicted exercise capacity >85% (group B). Group A patients had a higher prevalence of myocardial ischemia (43% vs 30%, . P=.0005), 2- or 3-vessel obstructive CAD (38% vs 18%, . P=.001), myocardial infarction (17% vs 9%, . P=.004), death (10% vs 4%, . P=.008), and myocardial infarction or stroke or death at 47-month follow-up (21% vs 12%, . P=.001). Stepwise Cox regression analysis showed that the only significant independent predictor for the time to development of myocardial infarction or stroke or death was a predicted exercise capacity >85% (hazard ratio, 0.52; 95% confidence interval, 0.34-0.78; . P=.002). Diabetic persons with a predicted exercise capacity >85% had a 48% lower chance of myocardial infarction, stroke, or death than those with a predicted exercise capacity ≤85%.
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U2 - 10.1111/j.1751-7141.2009.00051.x
DO - 10.1111/j.1751-7141.2009.00051.x
M3 - Article
C2 - 20021621
AN - SCOPUS:72549094037
SN - 1520-037X
VL - 13
SP - 14
EP - 17
JO - Preventive Cardiology
JF - Preventive Cardiology
IS - 1
ER -