IncobotulinumtoxinA (Xeomin): background, mechanism of action, and manufacturing.

Z. Paul Lorenc, Jeffrey M. Kenkel, Steven Fagien, Haideh Hirmand, Mark S. Nestor, Anthony P. Sclafani, Jonathan M. Sykes, Heidi A. Waldorf

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

IncobotulinumtoxinA is the third botulinum neurotoxin type A (BoNTA) to be approved for aesthetic use in the United States. This article introduces the new product with an overview of clinical applications and a discussion of the neurotoxin's molecular structure. The role and clinical relevance of complexing proteins in BoNTA products are discussed. Finally, incobotulinumtoxinA's mechanism of action is described.

Original languageEnglish (US)
JournalAesthetic surgery journal / the American Society for Aesthetic Plastic surgery
Volume33
Issue number1 Suppl
DOIs
StatePublished - Mar 2013

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Type A Botulinum Toxins
Neurotoxins
Molecular Structure
Esthetics
Proteins
incobotulinumtoxinA

ASJC Scopus subject areas

  • Medicine(all)

Cite this

IncobotulinumtoxinA (Xeomin) : background, mechanism of action, and manufacturing. / Lorenc, Z. Paul; Kenkel, Jeffrey M.; Fagien, Steven; Hirmand, Haideh; Nestor, Mark S.; Sclafani, Anthony P.; Sykes, Jonathan M.; Waldorf, Heidi A.

In: Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery, Vol. 33, No. 1 Suppl, 03.2013.

Research output: Contribution to journalArticle

Lorenc, Z. Paul ; Kenkel, Jeffrey M. ; Fagien, Steven ; Hirmand, Haideh ; Nestor, Mark S. ; Sclafani, Anthony P. ; Sykes, Jonathan M. ; Waldorf, Heidi A. / IncobotulinumtoxinA (Xeomin) : background, mechanism of action, and manufacturing. In: Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery. 2013 ; Vol. 33, No. 1 Suppl.
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