TY - JOUR
T1 - Increased survival of persons with tuberculosis and human immunodeficiency virus infection, 1991-2000
AU - Leonard, Michael K.
AU - Larsen, Nina
AU - Drechsler, Henning
AU - Blumberg, Henry
AU - Lennox, Jeffrey L.
AU - Arrellano, Martha
AU - Filip, Jennifer
AU - Horsburgh, C. Robert
PY - 2002/4/1
Y1 - 2002/4/1
N2 - To determine factors associated with the occurrence of human immunodeficiency virus (HIV) infection and tuberculosis (TB) disease (HIV-TB) and the associated survival rate, we analyzed patients with HIV-TB at Grady Memorial Hospital, Atlanta, Georgia, from 1991 through 2000. Overall, 644 patients with HIV-TB were seen. The number of HIV-TB cases per year was highest in 1992 (102 cases) and declined to 39 cases in 2000. Over time, patients were more likely to be enrolled in the HIV outpatient clinic (P<. 01), but, in 1997, only 21 (51%) of 41 patients were enrolled in HIV-infection care programs and only 9 (22%) of 41 received HAART. The 1-year survival rate for patients with HIV-TB was 58% in 1991, 81% in 1994, and 83% in 1997 (P<. 001). The increase in survival for patients with HIV-TB between 1991 and 1994 was likely due to improved TB and HIV therapy. More effective strategies for enrolling and maintaining HIV-TB patients in HIV-infection care programs could further increase survival.
AB - To determine factors associated with the occurrence of human immunodeficiency virus (HIV) infection and tuberculosis (TB) disease (HIV-TB) and the associated survival rate, we analyzed patients with HIV-TB at Grady Memorial Hospital, Atlanta, Georgia, from 1991 through 2000. Overall, 644 patients with HIV-TB were seen. The number of HIV-TB cases per year was highest in 1992 (102 cases) and declined to 39 cases in 2000. Over time, patients were more likely to be enrolled in the HIV outpatient clinic (P<. 01), but, in 1997, only 21 (51%) of 41 patients were enrolled in HIV-infection care programs and only 9 (22%) of 41 received HAART. The 1-year survival rate for patients with HIV-TB was 58% in 1991, 81% in 1994, and 83% in 1997 (P<. 001). The increase in survival for patients with HIV-TB between 1991 and 1994 was likely due to improved TB and HIV therapy. More effective strategies for enrolling and maintaining HIV-TB patients in HIV-infection care programs could further increase survival.
UR - http://www.scopus.com/inward/record.url?scp=0036532219&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036532219&partnerID=8YFLogxK
U2 - 10.1086/339448
DO - 10.1086/339448
M3 - Article
C2 - 11880967
AN - SCOPUS:0036532219
SN - 1058-4838
VL - 34
SP - 1002
EP - 1007
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 7
ER -