Increasing our understanding of pigmentary disorders

Pearl Grimes, James J. Nordlund, Amit G. Pandya, Susan Taylor, Marta Rendon, Jean Paul Ortonne

Research output: Contribution to journalArticle

47 Scopus citations


This article focuses on developments in pigmentary disorders that extend dermatologists' understanding of the field. Areas that are reviewed include the basic biochemistry, pharmacology, and physiology of the melanocortin system; melanosome development; genetic diseases associated with pigmentary disorders; pigmentary disorders secondary to systemic disease; drug-induced hyperpigmentation; environmental exposure to chemicals; and primary disorders of hyperpigmentation such as melasma and lentigines. Basic, clinical, and epidemiological research, along with a number of clinical case reports, were included in the review. This article also reports on the new health-related quality-of-life instrument (MELASQOL) that has been developed for women with melasma.

Original languageEnglish (US)
JournalJournal of the American Academy of Dermatology
Issue number5 SUPPL. 2
Publication statusPublished - May 2006


ASJC Scopus subject areas

  • Dermatology

Cite this

Grimes, P., Nordlund, J. J., Pandya, A. G., Taylor, S., Rendon, M., & Ortonne, J. P. (2006). Increasing our understanding of pigmentary disorders. Journal of the American Academy of Dermatology, 54(5 SUPPL. 2).