Indole diterpenoid synthetic studies. Construction of the heptacyclic core of (-)-nodulisporic acid D

Amos B. Smith, Akin H. Davulcu, László Kürti

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Construction of the heptacyclic core of (-)-nodulisporic acid D, a representative member of a recently discovered class of architecturally complex, ectoparasiticidal indole alkaloids, has been achieved. The modular synthetic strategy comprises an expedient, stereocontrolled synthesis of a tricyclic western hemisphere, in conjunction with union of an eastern hemisphere, exploiting the 2-substituted indole synthetic protocol introduced and developed in our laboratory.

Original languageEnglish (US)
Pages (from-to)1669-1672
Number of pages4
JournalOrganic Letters
Volume8
Issue number8
DOIs
StatePublished - Apr 13 2006

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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