Inducamides A-C, chlorinated alkaloids from an RNA polymerase mutant strain of Streptomyces sp.

Peng Fu, Matthew Jamison, Scott La, John B. MacMillan

Research output: Contribution to journalArticle

28 Scopus citations


Inducamides A-C (1-3), three new chlorinated alkaloids featuring an amide skeleton generated by a tryptophan fragment and a 6-methylsalicylic acid unit, were isolated from a chemically induced mutant strain of Streptomyces sp. with the inducamides only being produced in the mutant strain. Their structures, including stereochemistry, were determined by spectroscopic analysis, Marfey's method, and CD spectroscopy.

Original languageEnglish (US)
Pages (from-to)5656-5659
Number of pages4
JournalOrganic Letters
Issue number21
StatePublished - Nov 7 2014


ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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