Induction of myosin light chain synthesis in heterokaryons between normal diploid cells

Woodring E. Wright

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Quail myoblasts were maintained in an undifferentiated state by first blocking differentiation with 5-bromodeoxyuridine and then reversing the block in the presence of phorbol-12-myristate-13-acetate. The synthesis of quail skeletal myosin light chain 1 is induced in heterokaryons formed by fusing these undifferentiated quail myoblasts to differentiated chick myocytes. These results extend observations previously obtained using an established line of rat myoblasts and indicate that the induction is a result of regulatory interactions present in normal diploid cells.

Original languageEnglish (US)
Pages (from-to)851-858
Number of pages8
JournalIn Vitro - Plant
Volume18
Issue number10
DOIs
StatePublished - Oct 1 1982

Keywords

  • cell fusion
  • differentiation
  • heterokaryons
  • induction
  • myogenesis

ASJC Scopus subject areas

  • Biotechnology
  • Plant Science

Fingerprint Dive into the research topics of 'Induction of myosin light chain synthesis in heterokaryons between normal diploid cells'. Together they form a unique fingerprint.

Cite this