Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

Christina R. Robinson; Justin L. Martin; Lily Zhang; Russell M. Canham; Shuaib M Abdullah; Joaquin E. Cigarroa; L. David Hillis; Sabina A. Murphy; Darren K McGuire; James A de Lemos; Ellen C. Keeley

doi:10.1016/j.amjcard.2005.07.103

Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

Christina R. Robinson, Justin L. Martin, Lily Zhang, Russell M. Canham, Shuaib M Abdullah, Joaquin E. Cigarroa, L. David Hillis, Sabina A. Murphy, Darren K McGuire, James A de Lemos, Ellen C. Keeley

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

Original language	English (US)
Pages (from-to)	7-9
Number of pages	3
Journal	American Journal of Cardiology
Volume	97
Issue number	1
DOIs	https://doi.org/10.1016/j.amjcard.2005.07.103
State	Published - Jan 1 2006

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.amjcard.2005.07.103

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Robinson, C. R., Martin, J. L., Zhang, L., Canham, R. M., Abdullah, S. M., Cigarroa, J. E., Hillis, L. D., Murphy, S. A., McGuire, D. K., de Lemos, J. A., & Keeley, E. C. (2006). Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction. American Journal of Cardiology, 97(1), 7-9. https://doi.org/10.1016/j.amjcard.2005.07.103

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title = "Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction",

abstract = "In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.",

author = "Robinson, {Christina R.} and Martin, {Justin L.} and Lily Zhang and Canham, {Russell M.} and Abdullah, {Shuaib M} and Cigarroa, {Joaquin E.} and Hillis, {L. David} and Murphy, {Sabina A.} and McGuire, {Darren K} and {de Lemos}, {James A} and Keeley, {Ellen C.}",

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T1 - Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

AU - Robinson, Christina R.

AU - Martin, Justin L.

AU - Zhang, Lily

AU - Canham, Russell M.

AU - Abdullah, Shuaib M

AU - Cigarroa, Joaquin E.

AU - Hillis, L. David

AU - Murphy, Sabina A.

AU - McGuire, Darren K

AU - de Lemos, James A

AU - Keeley, Ellen C.

PY - 2006/1/1

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N2 - In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

AB - In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

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Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

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