Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

Christina R. Robinson, Justin L. Martin, Lily Zhang, Russell M. Canham, Shuaib M Abdullah, Joaquin E. Cigarroa, L. David Hillis, Sabina A. Murphy, Darren K McGuire, James A de Lemos, Ellen C. Keeley

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

Original languageEnglish (US)
Pages (from-to)7-9
Number of pages3
JournalAmerican Journal of Cardiology
Volume97
Issue number1
DOIs
StatePublished - Jan 1 2006

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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