Infections of the central nervous system.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Infections of the central nervous system are common, serious medical conditions. One hundred consecutive adult cases with purulent meningitis of known etiology encountered by the Medical Service at Parkland Memorial Hospital were reviewed. Streptococcus pneumoniae was the most common pathogen (56 cases), followed by Neisseria meningitidis (16 cases) and Listeria monocytogenes (seven cases). Hemophilus influenzae, Staphylococcus aureus, and streptococci each accounted for five cases. An additional 15 patients had purulent meningitis with a pathogen being isolated. Twenty five purulent meningitis cases of known etiology after trauma or neurosurgery were reviewed. Staphylococcus aureus (five cases), Staphylococcus epidermidis (four cases), and gram negative bacilli (14 cases) were the most common pathogens. Review of intracranial suppurative infections demonstrated advances in microbiology, antibiotic therapy, and imaging, leading to improvements in therapy. Subdural empyema continues to be a difficult diagnosis to make and apparently is related to the anatomic pathology of the infectious process. To illustrate salient features about granulomatous meningitis and encephalitis, cases of tuberculous meningitis, herpes simplex encephalitis, St. Louis encephalitis, and encephalitis of undetermined etiology are presented and discussed.

Original languageEnglish (US)
Pages (from-to)379-391
Number of pages13
JournalAmerican Journal of the Medical Sciences
Volume304
Issue number6
StatePublished - Dec 1992

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Central Nervous System Infections
Meningitis
Encephalitis
Staphylococcus aureus
St. Louis Encephalitis
Subdural Empyema
Herpes Simplex Encephalitis
Meningeal Tuberculosis
Neisseria meningitidis
Staphylococcus epidermidis
Haemophilus influenzae
Listeria monocytogenes
Neurosurgery
Streptococcus pneumoniae
Microbiology
Streptococcus
Bacillus
Pathology
Anti-Bacterial Agents
Wounds and Injuries

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Infections of the central nervous system. / Luby, J. P.

In: American Journal of the Medical Sciences, Vol. 304, No. 6, 12.1992, p. 379-391.

Research output: Contribution to journalArticle

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