Inflammatory Biomarkers of Birth Asphyxia

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Although therapies in addition to whole-body cooling are being developed to treat the neonate at risk for hypoxic-ischemic encephalopathy, we have no quickly measured serum inflammatory or neuronal biomarkers to acutely and accurately identify brain injury or to follow the efficacy of therapy. This review covers inflammatory serum biomarkers in the setting of birth asphyxia that can help assess the degree or severity of encephalopathy at birth and neurodevelopmental outcomes. These biomarkers still need to be independently validated in large cohorts before they are ready for clinical implementation in practice.

Original languageEnglish (US)
Pages (from-to)501-510
Number of pages10
JournalClinics in Perinatology
Volume43
Issue number3
DOIs
StatePublished - Sep 1 2016

Keywords

  • Asphyxia
  • Cytokines
  • GFAP
  • Placenta
  • Ubiquitin

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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