Inflammatory myofibroblastic tumor as a second neoplasm after Wilms tumor

Michael V. Ortiz, Christopher T. Rossi, D. Ashley Hill, Phillip C. Guzzetta, Faisal Qureshi, Jeffrey S. Dome

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report two survivors of Wilms tumor (WT) who developed inflammatory myofibroblastic tumor (IMT). The first patient had IMT in the mainstem bronchus 1 year after WT therapy that included vincristine, dactinomycin, doxorubicin (VDA) and whole lung radiation therapy (XRT). The second patient had IMT in the cecum 7 years after WT therapy consisting of VDA and abdominal XRT. The unlikely co-occurrence of WT and IMT suggests a genetic link between these tumors or that IMT can arise as a complication of cancer therapy. IMT should be considered in WT survivors who develop secondary tumors, especially at unusual sites.

Original languageEnglish (US)
Pages (from-to)1075-1077
Number of pages3
JournalPediatric Blood and Cancer
Volume62
Issue number6
DOIs
StatePublished - Jan 1 2015

Fingerprint

Second Primary Neoplasms
Wilms Tumor
Neoplasms
Dactinomycin
Vincristine
Doxorubicin
Survivors
Cecum
Bronchi
Radiotherapy
Therapeutics
Lung

Keywords

  • ALK
  • Inflammatory myofibroblastic tumor
  • Second neoplasm
  • Wilms tumor

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Cite this

Ortiz, M. V., Rossi, C. T., Hill, D. A., Guzzetta, P. C., Qureshi, F., & Dome, J. S. (2015). Inflammatory myofibroblastic tumor as a second neoplasm after Wilms tumor. Pediatric Blood and Cancer, 62(6), 1075-1077. https://doi.org/10.1002/pbc.25345

Inflammatory myofibroblastic tumor as a second neoplasm after Wilms tumor. / Ortiz, Michael V.; Rossi, Christopher T.; Hill, D. Ashley; Guzzetta, Phillip C.; Qureshi, Faisal; Dome, Jeffrey S.

In: Pediatric Blood and Cancer, Vol. 62, No. 6, 01.01.2015, p. 1075-1077.

Research output: Contribution to journalArticle

Ortiz, MV, Rossi, CT, Hill, DA, Guzzetta, PC, Qureshi, F & Dome, JS 2015, 'Inflammatory myofibroblastic tumor as a second neoplasm after Wilms tumor', Pediatric Blood and Cancer, vol. 62, no. 6, pp. 1075-1077. https://doi.org/10.1002/pbc.25345
Ortiz, Michael V. ; Rossi, Christopher T. ; Hill, D. Ashley ; Guzzetta, Phillip C. ; Qureshi, Faisal ; Dome, Jeffrey S. / Inflammatory myofibroblastic tumor as a second neoplasm after Wilms tumor. In: Pediatric Blood and Cancer. 2015 ; Vol. 62, No. 6. pp. 1075-1077.
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