Influence of a new prophylactic antibiotic therapy on the incidence of liver abscesses after chemoembolization treatment of liver tumors

Jean Francois H Geschwind, Shaifali Kaushik, Douglas E. Ramsey, Michael A. Choti, Elliot K. Fishman, Hicham Kobeiter

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Abstract

Intrahepatic abscess is a complication of transcatheter arterial chemoembolization (TACE) treatment in patients who have a history of biliary reconstructive surgery. This study followed eight patients who underwent chemoembolization after biliary surgery. These patients were divided into two groups. Patients in group one (n = 4) were administered intravenous cephalexin for prophylaxis. Patients in group two (n = 4) were administered bowel preparation and tazobactam/piperacillin. All patients in group one developed hepatic abscesses, which were treated with percutaneous catheter drainage and antibiotics. None of the patients in group two developed abscesses. Aggressive antibiotic prophylaxis with bowel preparation may provide protection against intrahepatic abscesses after chemoembolization in patients who have a history of biliary reconstructive surgery.

Original languageEnglish (US)
Pages (from-to)1163-1166
Number of pages4
JournalJournal of Vascular and Interventional Radiology
Volume13
Issue number11
Publication statusPublished - Nov 1 2002

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Keywords

  • Antibiotics
  • Liver neoplasms, chemoembolization
  • Liver, abscess

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Geschwind, J. F. H., Kaushik, S., Ramsey, D. E., Choti, M. A., Fishman, E. K., & Kobeiter, H. (2002). Influence of a new prophylactic antibiotic therapy on the incidence of liver abscesses after chemoembolization treatment of liver tumors. Journal of Vascular and Interventional Radiology, 13(11), 1163-1166.