TY - JOUR
T1 - Inhibition of cellular adhesiveness by sulfhydryl blocking agents
AU - Grinnell, F.
AU - Shere, P. A.
PY - 1971/8
Y1 - 1971/8
N2 - Rat hepatoma cells rapidly adhered to the polystyrene surfaces of culture bottles. The adhesiveness of the cells was inhibited by sulfhydryl blocking reagents including mercurials, arsenicals, and alkylating agents. Inhibition was prevented, and in some cases reversed, by the addition of dithiothreitol to the adhesive medium. The current model explaining cellular adhesion is discussed in the light of these observations.
AB - Rat hepatoma cells rapidly adhered to the polystyrene surfaces of culture bottles. The adhesiveness of the cells was inhibited by sulfhydryl blocking reagents including mercurials, arsenicals, and alkylating agents. Inhibition was prevented, and in some cases reversed, by the addition of dithiothreitol to the adhesive medium. The current model explaining cellular adhesion is discussed in the light of these observations.
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U2 - 10.1002/jcp.1040780119
DO - 10.1002/jcp.1040780119
M3 - Article
C2 - 4329388
AN - SCOPUS:0015108316
SN - 0021-9541
VL - 78
SP - 153
EP - 157
JO - Journal of cellular physiology
JF - Journal of cellular physiology
IS - 1
ER -